Evidence map›Paper›PMID 39678528›Full record

ArticleIranian journal of medical sciences2024

The Effect of Eight Weeks of High-Intensity Interval Training on Follistatin Gene Expression in the Fast and Slow Twitch Muscles of Rats with Myocardial Infarction.

Edris Ramezani, Mehran Ghahramani, Hadi Ghaedi

Abstract read
In one paragraph

Article in Iranian journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Edris RamezaniDepartment of Exercise Physiology, Lamerd Branch, Islamic Azad University, Lamerd, Iran.
Mehran GhahramaniDepartment of Exercise Physiology, Gilan-E-Gharb Branch, Islamic Azad University, Gilan-E-Gharb, Iran.
Hadi GhaediDepartment of Exercise Physiology, Lamerd Branch, Islamic Azad University, Lamerd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myocardial infarction causes mitochondrial atrophy and loss of function by reducing mitochondrial volume. Therefore, researchers are interested in finding a way to reduce the injuries and treat them. The study aims to evaluate the effect of 8 weeks of high-intensity interval training on follistatin (FST) gene expression in the fast and slow twitch muscles of rats with myocardial infarction. Methods: The study was conducted in 2020 at the Cardiac Research Center, Shahid Rajaei University of Medical Sciences (Tehran, Iran). For this purpose, 12 male Wistar rats with myocardial infarction were assigned to the experimental group high-intensity interval training (3 days a week for 30 min, each interval consisting of 4 min of running with 85-90% VO Results: Independent Conclusion: Overall, 8 weeks of intense intermittent exercise decreased FST gene expression in slow and fast twitch muscles in rats with myocardial infarction.

Indexed as

FollistatinHigh-Intensity Interval TrainingMyocardial InfarctionPhysical Conditioning, AnimalRats, WistarAnimalsDisease Models, AnimalGene ExpressionMaleMuscle Fibers, Fast-TwitchMuscle Fibers, Slow-TwitchMuscular AtrophyRatsFollistatinExerciseGene expressionMuscular atrophyMyocardial infarction

Identifiers

PMID39678528
PMCPMC11645421

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.