ArticleAmerican journal of translational research2024
Effect of body mass index on breast cancer prognosis: a focus on ER/PR status and subtype-specific recurrence risk.
Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo explore prognostic differences in breast cancer (BC) recurrence risk across estrogen receptor (ER) and progesterone receptor (PR) defined subtypes, stratified by body mass index (BMI) categories, aiming to identify potential mechanisms.
methodsA cohort of 358 breast cancer patients provided data on height, weight, menopausal status, and receptor profiles for analysis.
resultsOur findings highlighted that BMI's impact on BC prognosis was significantly influenced by ER/PR tumor status. In premenopausal women, BMI notably affected recurrence rates, especially in patients with ER-positive and PR-positive subtypes.
conclusionsAdjusting treatment strategies based on BMI across different menopausal statuses and tumor subtypes could improve outcome for patients with ER-positive/PR-positive tumors.
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