ArticleAmerican journal of translational research2024
Clinical observation of Danlou tablets combined with aspirin for phlegm and blood stasis syndrome in coronary heart disease: impact on related serum factors.
Article in American journal of translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo investigate the effect of Danlou tablets combined with aspirin for treating phlegm and blood stasis syndrome in coronary heart disease (CHD).
methodsThis study is a retrospective study, a total of 120 patients with phlegm and blood stasis syndrome with CHD were randomly assigned to either a control group (aspirin, 100 mg, once daily) or an observation group (Danlou tablets, 1.5 g, three times daily; aspirin, 100 mg, once daily) at a 1:1 ratio. Treatment was administered for 28 consecutive days. Pre- and post-treatment assessments included lipid profiles, hemorheology, inflammatory markers, serum phospholipase A2 (sPLA
resultsAfter 1 month of treatment, the observation group showed a significantly higher overall clinical efficacy rate (P = 0.038) compared to the control group. Post-treatment levels of sPLA
conclusionsThe combination of Danlou tablets and aspirin significantly improves clinical symptoms in CHD patients with phlegm and blood stasis syndrome, reduces serum sPLA
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