Evidence map›Paper›PMID 39678637›Full record

ReviewMycology2024

Recent developments in the production of prebiotic fructooligosaccharides using fungal fructosyltransferases.

Hemant Kumar Rawat, Suresh Nath, Isha Sharma, Naveen Kango

Abstract readReview
In one paragraph

Review in Mycology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hemant Kumar RawatDepartment of Microbiology, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, India.ORCID https://orcid.org/0000-0003-2138-769X
Suresh NathDepartment of Microbiology, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, India.
Isha SharmaDepartment of Microbiology, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, India.
Naveen KangoDepartment of Microbiology, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, India.ORCID https://orcid.org/0000-0003-0362-3599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prebiotic nutritional ingredients have received attention due to their health-promoting potential and related uses in the food and nutraceutical industries. Recent times have witnessed an increasing interest in the use of fructooligosaccharides (FOS) as prebiotics and their generation using microbial enzymes. FOS consumption is known to confer health benefits such as protection against colon cancer, improved mineral absorption, lowering effect on serum lipid and cholesterol concentration, antioxidant properties, favourable dietary modulation of the human colonic microbiota, and immuno-modulatory effects. Comparative analysis of molecular models of various fructosyltransferases (FTases) reveals the mechanism of action and interaction of substrate with the active site. Microbial FTases carry out transfructosylation of sucrose into fructooligosaccharides (kestose, nystose, and fructofuranosylnystose), the most predominantly used prebiotic oligosaccharides. Furthermore, FOS has also been used for other purposes, such as low-calorie sweeteners, dietary fibres, and as the substrates for fermentation. This review highlights the occurrence, characteristics, immobilisation, and potential applications of FOS-generating fungal FTases. Production, heterologous expression, molecular characteristics, and modelling of fungal FTases underpinning their biotechnological prospects are also discussed.

Indexed as

Fructooligosaccharides (FOS)fructosyltransferase (FTase)fungiimmobilisationprebioticprobiotic

Identifiers

PMID39678637
PMCPMC11636151

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.