Evidence mapPaperPMID 39679395Full record

ArticleBiomedical optics express2024

Photothermal optical coherence microscopy for studying lipid architecture in human carotid arteries.

Aaron Doug Deen, Antonio López-Marín, Jonas J M Riksen, Antonius F W van der Steen, Gijs van Soest

Abstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aaron Doug DeenDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, The Netherlands.ORCID https://orcid.org/0000-0002-1318-2136
Antonio López-MarínDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, The Netherlands.ORCID https://orcid.org/0000-0001-7936-4525
Jonas J M RiksenDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, The Netherlands.
Antonius F W van der SteenDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, The Netherlands.
Gijs van SoestDepartment of Cardiology, Cardiovascular Institute, Thorax Center, Erasmus MC, The Netherlands.ORCID https://orcid.org/0000-0001-6474-3100

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photothermal optical coherence microscopy (PT-OCM) combines the high-resolution, label-free morphological imaging of OCM with the ability to discriminate tissue composition through phase-sensitive photothermal imaging. In this study, we perform 2D imaging of human carotid endarterectomies to spectrally determine lipid distribution, with verification via histologically stained samples. The structural information from OCM is combined with the spectral information gained from measuring the resulting sample surface displacement from thermoelastic expansion, following light irradiation. PT-OCM is thus demonstrated as a potential tool in the investigation of atherosclerotic plaque lipids, contributing towards the understanding of plaque instability.

Identifiers

PMID39679395
PMCPMC11640572

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.