Evidence map›Paper›PMID 39680292›Full record

ArticleClinical and experimental nephrology2025

Factors associated with awareness of chronic kidney disease, and impact of awareness on renal prognosis.

Akiko Hattori, Takahiro Imaizumi, Takuya Toda, Daisuke Sakurai, Nami Takai, Takahiro Miki, Michitaka Maekawa, Sawako Kato, Yuta Hagiwara, Yasuko Yoshida and 1 more

Abstract read
In one paragraph

Article in Clinical and experimental nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Akiko Hattori *Department of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan.
Takahiro Imaizumi *Department of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan.
Takuya TodaPREVENT Inc., Nagoya, Japan.
Daisuke SakuraiPREVENT Inc., Nagoya, Japan.
Nami TakaiDepartment of Nursing, Nagoya University Hospital, Nagoya, Japan.
Takahiro MikiPREVENT Inc., Nagoya, Japan.
Michitaka MaekawaHidamari Kokoro Clinic, Nagoya, Japan.
Sawako KatoDepartment of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan.
Yuta HagiwaraPREVENT Inc., Nagoya, Japan.
Yasuko YoshidaDepartment of Innovative Research Center for Preventive Medical Engineering, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shoichi MaruyamaDepartment of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan. marus@med.nagoya-u.ac.jp.ORCID http://orcid.org/0000-0002-8858-632X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) awareness could help prevent disease progression through modifiable risk factors. However, few patients with CKD are aware of their disease. We aimed to investigate the factors associated with CKD awareness and impact of CKD awareness on renal prognosis.

methodsWe investigated the proportion of participants with CKD who answered 'aware of CKD' in the questionnaire among those undergoing health check-ups from 2013 to 2022. Participants included working-age employees and their dependents covered by health insurance associations for large and medium-sized companies. The outcome was defined as the change from 'unaware' to 'aware' of CKD; multivariable logistic regression analysis assessed the association of urine tests or nutritional guidance with CKD awareness. A control group was randomly selected from the unaware group and matched for age, sex, estimated glomerular filtration rate (eGFR), urinary protein categories, and follow-up period. Changes in eGFR slopes before and after awareness were compared using linear mixed-effects models.

resultsOf the 13,489 participants, 2.8% were aware of CKD at baseline; of the 1,614 with CKD-related disease codes, only 19.6% were aware. The odds ratios of urine tests or nutritional guidance in relation to awareness occurrence were 1.98 (1.29-3.05) and 3.01 (1.38-6.53), respectively. The difference in the eGFR slope improvement from before to after CKD awareness was + 0.92 mL/min/1.73 m

conclusionOur findings suggest that urine tests and nutritional guidance may promote CKD awareness, which may help slow its progression.

Indexed as

AwarenessHealth Knowledge, Attitudes, PracticeKidneyRenal Insufficiency, ChronicAdultAgedDisease ProgressionFemaleGlomerular Filtration RateHumansMaleMiddle AgedPrognosisRisk FactorsSurveys and QuestionnairesAwarenessCKDeGFR slopeNutritional guidanceUrine tests

Identifiers

PMID39680292
PMCPMC12049403

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.