Evidence map›Paper›PMID 39680436›Full record

ArticleeLife2024

Distinct release properties of glutamate/GABA co-transmission serve as a frequency-dependent filtering of supramammillary inputs.

Himawari Hirai, Kohtarou Konno, Miwako Yamasaki, Masahiko Watanabe, Takeshi Sakaba, Yuki Hashimotodani

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Himawari HiraiGraduate School of Brain Science, Doshisha University, Kyoto, Japan.
Kohtarou KonnoDepartment of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo, Japan.
Miwako YamasakiDepartment of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo, Japan.ORCID https://orcid.org/0000-0003-4974-9349
Masahiko WatanabeDepartment of Anatomy, Faculty of Medicine, Hokkaido University, Sapporo, Japan.ORCID https://orcid.org/0000-0001-5037-7138
Takeshi SakabaGraduate School of Brain Science, Doshisha University, Kyoto, Japan.ORCID https://orcid.org/0000-0003-0688-7717
Yuki HashimotodaniGraduate School of Brain Science, Doshisha University, Kyoto, Japan.ORCID https://orcid.org/0000-0001-6723-2736

Funding

Japan Society for the Promotion of Science JP20H03358Japan Society for the Promotion of Science JP20KK0171Japan Society for the Promotion of Science JP23H04240Japan Society for the Promotion of Science JP23K18167Japan Society for the Promotion of Science JP24K02125Japan Society for the Promotion of Science JP24KJ2139Japan Society for the Promotion of Science JSPS Core-to-Core Program A. Advanced Research Networks JPJSCCA20220007Japan Society for the Promotion of Science Platforms for Advanced Technologies and Research Resources "Advanced Bioimaging Support" JP22H04926Takeda Science Foundation Bioscience and Specific Research GrantsTakeda Science Foundation Medical Research Continuous Grants
6 · The paper itself

Abstract

Glutamate and GABA co-transmitting neurons exist in several brain regions; however, the mechanism by which these two neurotransmitters are co-released from the same synaptic terminals remains unclear. Here, we show that the supramammillary nucleus (SuM) to dentate granule cell synapses, which co-release glutamate and GABA, exhibit differences between glutamate and GABA release properties in paired-pulse ratio, Ca

Indexed as

gamma-Aminobutyric AcidGlutamic AcidSynaptic TransmissionAnimalsMaleNeuronsPresynaptic TerminalsRatsReceptors, N-Methyl-D-AspartateSynapsesSynaptic Vesiclesgamma-Aminobutyric AcidGlutamic AcidReceptors, N-Methyl-D-Aspartateco-releasedentate gyrushippocampusmouseneuroscienceshort-term plasticitysupramammillary nucleussynaptic transmission

Identifiers

PMID39680436
PMCPMC11649240

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.