Evidence map›Paper›PMID 39681603›Full record

ArticleScientific reports2024

Anogenital distance on MRI does not correlate to surgical diagnosis of endometriosis in patients without prior abdominal surgery.

Sebastian Harth, Lena Metze, Daniel Leufkens, Fritz C Roller, Alexander Brose, Felix Zeppernick, Ivo Meinhold-Heerlein, Gabriele A Krombach

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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sebastian HarthDepartment of Diagnostic and Interventional Radiology, University Hospital Gießen, Justus Liebig University of Gießen, Klinikstr. 33, 35392, Giessen, Germany. Sebastian.Harth@radiol.med.uni-giessen.de.
Lena MetzeDepartment of Diagnostic and Interventional Radiology, University Hospital Gießen, Justus Liebig University of Gießen, Klinikstr. 33, 35392, Giessen, Germany.
Daniel LeufkensDepartment of Medicine, Institute of Medical Informatics, Justus Liebig University of Gießen, Rudolf-Buchheim-Straße 6, 35392, Giessen, Germany.
Fritz C RollerDepartment of Diagnostic and Interventional Radiology, University Hospital Gießen, Justus Liebig University of Gießen, Klinikstr. 33, 35392, Giessen, Germany.
Alexander BroseDepartment of Diagnostic and Interventional Radiology, University Hospital Gießen, Justus Liebig University of Gießen, Klinikstr. 33, 35392, Giessen, Germany.
Felix ZeppernickDepartment of Gynecology and Obstetrics, University Hospital Gießen, Justus Liebig University of Gießen, Klinikstr. 33, 35392, Giessen, Germany.
Ivo Meinhold-HeerleinDepartment of Gynecology and Obstetrics, University Hospital Gießen, Justus Liebig University of Gießen, Klinikstr. 33, 35392, Giessen, Germany.
Gabriele A KrombachDepartment of Diagnostic and Interventional Radiology, University Hospital Gießen, Justus Liebig University of Gießen, Klinikstr. 33, 35392, Giessen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anogenital distance (AGD) is regarded as a potential biomarker for endometriosis, and a measurement on MRI images has been found to be promising. This study aimed to evaluate the measurement of AGD on MRI to predict the surgical diagnosis of endometriosis. We included 127 patients who received an MRI for endometriosis between October 2018 and February 2023. AGD was measured on MRI by two readers (MRI-AGD-AC: clitoris to anus; MRI-AGD-AF: posterior fourchette to anus). The feasibility and interobserver reliability of AGD measurements were evaluated. Differences in AGD between patient groups were analyzed. The intraclass correlation coefficient estimates indicated a good to excellent reliability of MRI-AGD-AC (0.92; 95% CI: 0.83-0.95) and a poor to good reliability of MRI-AGD-AF (0.68; 95% CI: 0.27-0.83). No statistically significant differences in the mean MRI-AGD-AC and MRI-AGD-AF in patients with and without surgical diagnosis of DIE (p = 0.413; p = 0.110), peritoneal endometriosis with and without DIE (p = 0.641; p = 0.323), and ovarian endometriosis (p = 0.155; p = 0.150) were found. The AUC ranged from 0.475 (95% CI: 0.365-0.584) to 0.586 (95% CI: 0.454-0.718). Thus, AGD does not constitute a valuable biomarker for patients with clinically suspected endometriosis.

Indexed as

EndometriosisMagnetic Resonance ImagingAdultAnal CanalFemaleGenitalia, FemaleHumansMiddle AgedReproducibility of ResultsRetrospective StudiesBiomarkersDiagnostic imagingEndometriosisMagnetic resonance imagingPelvic Pain

Identifiers

PMID39681603
PMCPMC11649681

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.