Evidence map›Paper›PMID 39682688›Full record

ArticleCells2024

A Novel Class of FKBP12 Ligands Rescues Premature Aging Phenotypes Associated with Myotonic Dystrophy Type 1.

Mikel García-Puga, Gorka Gerenu, Ariadna Bargiela, Jorge Espinosa-Espinosa, Laura Mosqueira-Martín, Maialen Sagartzazu-Aizpurua, Jesús M Aizpurua, Ainara Vallejo-Illarramendi, Rubén Artero, Adolfo López de Munain and 1 more

Abstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mikel García-PugaCellular Oncology Group, Biogipuzkoa Health Research Institute, Paseo Dr. Beguiristain s/n, 20014 San Sebastian, Spain.ORCID 0000-0002-2975-934X
Gorka GerenuNeuroscience Area, Biogipuzkoa Health Research Institute, Biodonostia Institute, 20014 San Sebastian, Spain.ORCID 0000-0002-4981-5791
Ariadna BargielaTranslational Genomics Group, University Institute for Biotechnology and Biomedicine (BIOTECMED), University of Valencia, 46100 Burjasot, Spain.ORCID 0000-0003-4336-2522
Jorge Espinosa-EspinosaTranslational Genomics Group, University Institute for Biotechnology and Biomedicine (BIOTECMED), University of Valencia, 46100 Burjasot, Spain.ORCID 0000-0003-0098-5201
Laura Mosqueira-MartínNeuroscience Area, Biogipuzkoa Health Research Institute, Biodonostia Institute, 20014 San Sebastian, Spain.ORCID 0000-0002-5714-7682
Maialen Sagartzazu-AizpuruaJoxe Mari Korta R&D Center, Department of Organic Chemistry I, University of the Basque Country, 20014 San Sebastian, Spain.
Jesús M AizpuruaJoxe Mari Korta R&D Center, Department of Organic Chemistry I, University of the Basque Country, 20014 San Sebastian, Spain.ORCID 0000-0002-1053-5776
Ainara Vallejo-IllarramendiNeuroscience Area, Biogipuzkoa Health Research Institute, Biodonostia Institute, 20014 San Sebastian, Spain.ORCID 0000-0002-2409-8263
Rubén ArteroTranslational Genomics Group, University Institute for Biotechnology and Biomedicine (BIOTECMED), University of Valencia, 46100 Burjasot, Spain.ORCID 0000-0003-1596-047X
Adolfo López de MunainNeuroscience Area, Biogipuzkoa Health Research Institute, Biodonostia Institute, 20014 San Sebastian, Spain.ORCID 0000-0002-9509-4032
Ander MatheuCellular Oncology Group, Biogipuzkoa Health Research Institute, Paseo Dr. Beguiristain s/n, 20014 San Sebastian, Spain.

Funding

Carlos III Institute PI22/01905
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aging, PrematureFibroblastsMyotonic DystrophyPhenotypeTacrolimus Binding Protein 1AAnimalsCalciumCell ProliferationCell SurvivalDisease Models, AnimalHumansLigandsMaleOxidative StressCalciumLigandsTacrolimus Binding Protein 1Aextended longevityFKBP12/RyR interactionmultisystem recoverymyotonic dystrophyoxidative stress

Identifiers

PMID39682688
PMCPMC11639790

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.