Evidence map›Paper›PMID 39682696›Full record

ReviewCells2024

How to Use Macrophages Against Cancer.

Jacek Kuźnicki, Natalia Janicka, Barbara Białynicka-Birula, Wojciech Kuźnicki, Hanna Chorążyczewska, Iwona Deszcz, Julita Kulbacka

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Macrophages: sentinels, warriors, and healers.Human molecular genetics · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jacek KuźnickiStudents Scientific Group No.148, Faculty of Medicine, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Natalia JanickaStudents Scientific Group No.148, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Barbara Białynicka-BirulaStudents Scientific Group No.148, Faculty of Medicine, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.ORCID 0009-0006-1472-3746
Wojciech KuźnickiDepartment of External Beam Radiotherapy, Nicolaus Copernicus Multidisciplinary Centre for Oncology and Traumatology, Pabianicka 62, 93-513 Łódź, Poland.
Hanna ChorążyczewskaStudents Scientific Group No.148, Faculty of Medicine, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Iwona DeszczDepartment of Immunopathology and Molecular Biology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.ORCID 0000-0003-1668-9458
Julita KulbackaDepartment of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.ORCID 0000-0001-8272-5440

Funding

Statutory Subsidy Funds of the Department of Molecular and Cellular Biology SUBZ.D260.24.076
6 · The paper itself

Abstract

Numerous studies have demonstrated the significant influence of immune cells on cancer development and treatment. This study specifically examines tumor-associated macrophages (TAMs), detailing their characteristics and roles in tumorigenesis and analyzing the impact of the ratio of TAM subtypes on patient survival and prognosis. It is established that TAMs interact with immunotherapy, radiotherapy, and chemotherapy, thereby influencing the efficacy of these treatments. Emerging therapies are explored, such as the use of nanoparticles (NPs) for drug delivery to target TAMs and modify the tumor microenvironment (TME). Additionally, novel anticancer strategies like the use of chimeric antigen receptor macrophages (CAR-Ms) show promising results. Investigations into the training of macrophages using magnetic fields, plasma stimulation, and electroporation are also discussed. Finally, this study presents prospects for the combination of TAM-based therapies for enhanced cancer treatment outcomes.

Indexed as

NeoplasmsTumor-Associated MacrophagesTumor MicroenvironmentAnimalsHumansImmunotherapyNanoparticlescancer immunotherapycombined cancer therapiesTAM subtype impacttumor-associated macrophages (TAMs)tumor microenvironment (TME)

Identifiers

PMID39682696
PMCPMC11639767

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.