Evidence map›Paper›PMID 39682698›Full record

ReviewCells2024

Mucosal Inflammatory Memory in Chronic Rhinosinusitis.

Min-Seok Koo, Sungmin Moon, Min-Seok Rha

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Min-Seok KooDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0009-0003-9115-9112
Sungmin MoonDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-1142-2079
Min-Seok RhaDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-1426-7534

Funding

Korea Health Industry Development Institute HI23C1464
6 · The paper itself

Abstract

Recent advancements in medical management, endoscopic sinus surgery, and biologics have significantly improved outcomes for patients with chronic rhinosinusitis (CRS). However, long-term recurrence is frequently observed following endoscopic sinus surgery, with symptoms worsening after biologics are discontinued. Consequently, refractory or recurrent CRS remains a significant challenge, causing a substantial healthcare burden. In this review, we provide current insights into mucosal inflammatory memory, a potential mechanism leading to CRS recurrence. Given that both immune and non-immune cells in the sinonasal mucosa play critical roles in the pathophysiology of CRS, a deeper understanding of the mechanisms underlying mucosal inflammatory memory in various cellular components of sinonasal tissue could aid in the management of refractory CRS. We describe and discuss the latest knowledge regarding the novel concept of inflammatory memory, including both adaptive immune memory and trained immunity. Additionally, we summarize the pathogenic memory features of the sinonasal mucosa cellular components in the context of CRS.

Indexed as

Nasal MucosaRhinitisSinusitisAnimalsChronic DiseaseHumansImmunologic MemoryInflammationRhinosinusitischronic rhinosinusitisinflammatory memorymucosal immunitytrained immunity

Identifiers

PMID39682698
PMCPMC11639807

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.