Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07287514 (Role of Linoleic Acid in Cardiometabolic Health Beyond Its Lipid-lowering Effects, and Its Dietary and Pathophysiological Implications), which is not on this map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
NCT07287514 narecruitingnot on this mapstarted 2025, after this paper: background citation
Role of Linoleic Acid in Cardiometabolic Health Beyond Its Lipid-lowering Effects, and Its Dietary and Pathophysiological Implications
TypeinterventionalSponsorPontificia Universidad Catolica de ChileRan2025 to 2026Enrolled120ConditionsInsulin Resistance, Metabolic DiseaseArmsLinoleic Acid-Rich Oil, Blend Oil
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors.
Loni BerkowitzDepartment of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8330077, Chile.
Guadalupe EcheverríaDepartment of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8330077, Chile.
Cristian SalazarDepartment of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8330077, Chile.ORCID 0009-0007-3575-2113
Cristian FaúndezDepartment of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8330077, Chile.
Christopher L CoeDepartment of Psychology, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-9335-9060
Carol RyffDepartment of Psychology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Attilio RigottiDepartment of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8330077, Chile.ORCID 0000-0002-0495-3525
Funding
University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
STATISTICS COREP01AG020166 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI RYFF, CAROL D. · 2002 to 2015
$50.6M
ZDV &3TC NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFECTED INFANTS &M01RR000865 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WASHINGTON, ARNOLD E. · 1985 to 2011
$43.4M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Integrative Pathways to Cognitive, Affective, and Brain HealthU01AG077928 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sterling C Johnson, MARGIE E LACHMAN · 2022 to 2026
$17.7M
WIHS INTENSIVE PHARMACOKINETIC STUDY (IPS)M01RR023942 · NCRR · GEORGETOWN UNIVERSITY · PI FEDEROFF, HOWARD J. · 2007 to 2009
$6.9M
Fondo Nacional de Desarrollo Científico y Tecnológico 11240454Fondo Nacional de Desarrollo Científico y Tecnológico 3210391Georgetown University M01-RR023942NCATS NIH HHS UL1 TR002373NCRR NIH HHS M01 RR000865NCRR NIH HHS M01 RR023942NCRR NIH HHS UL1 RR025011NIA NIH HHS P01 AG020166NIA NIH HHS P01-AG020166NIA NIH HHS U01 AG077928NIA NIH HHS U19 AG051426NIA NIH HHS U19-AG051426University of California, Los Angeles M01-RR00865University of Washington 1UL1RR025011
6 · The paper itself
Abstract
backgroundThe aim of this study was to identify the blood lipidomic profile associated with a healthy eating pattern in a middle-aged US population sample and to determine its relationship with metabolic disorders and cardiovascular risk (CVR). METHODOLOGY: Self-reported information about diet and blood samples were obtained from 2114 adult participants in the Midlife in the United States study (MIDUS). Food intake data were used to design a Healthy Diet Index (MIDUS-HEI) and to evaluate the predictive value by examining its association with health variables. The associated lipid signature (HEI-LS) was constructed using Lasso regression, from lipidomic data (LC/MS). Associations between HEI-LS, cardiometabolic biomarkers, and estimated CVR were assessed using multiple linear regression.
resultsMIDUS-HEI score was a robust indicator of dietary quality and inversely associated with body mass index (
conclusionsThe MIDUS-HEI effectively assessed dietary quality, confirming the link between poor diet quality and metabolic disorders in American population. Lipidomic profiling offered an objective assessment of dietary patterns and provided insights into the relationship between diet quality, metabolic responses, and CVR. This approach supports precision nutrition strategies for at-risk populations.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Lipidomic Signature of Healthy Diet Adherence and Its Association with Cardiometabolic Risk in American Adults. · full record | Socratic