Evidence map›Paper›PMID 39683512›Full record

SynthesisNutrients2024

Impact of Acute Lymphoblastic Leukaemia Treatment on the Nutritional Status of Paediatric Patients: A Systematic Review.

Rosaura Picáns-Leis, Fátima Nieto, Anabel Romero-Agrelo, Isabel Izquierdo-López, Lucía Rivas-Rodríguez, Rocío Vázquez-Cobela, Rosaura Leis

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rosaura Picáns-LeisNeonatology Department, University Clinical Hospital of Santiago de Compostela, Santiago de Compostela University, 15706 Santiago de Compostela, Spain.ORCID 0000-0003-4702-9962
Fátima NietoHealth Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.ORCID 0009-0002-9763-6445
Anabel Romero-AgreloHealth Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Isabel Izquierdo-LópezHealth Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Lucía Rivas-RodríguezHealth Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Rocío Vázquez-CobelaHealth Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.ORCID 0000-0002-3155-1601
Rosaura LeisHealth Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.ORCID 0000-0002-0540-4210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAcute lymphoblastic leukaemia (ALL) is the most prevalent cancer in childhood and is one of the leading causes of death annually. Antineoplastic treatments are associated with a high risk of malnutrition, which is important for continuous growth and development.

objectiveThis systematic review aimed to evaluate the effect of these treatments on the nutritional status of paediatric patients with ALL. Data were collected from the PubMed, Scopus, and Web of Science databases following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method. All the studies in which nutritional status was assessed in human beings diagnosed with ALL up to 18 years and published in English or Spanish between January 1900 and December 2023 were included.

resultsA total of 18 articles and 1692 participants were analysed in this review. Article quality was evaluated using the ROBINS-I tool. This systematic review has been registered on PROSPERO (CRD42024505111). ALL treatment has a negative impact on the nutritional status of these patients and played an important role in their growth and global development. ALL treatments can modify hunger perception and the palatability of food.

conclusionsNutritional status is important for patient prognosis and survival. Nutritional evaluation, a specific nutritional assessment, and follow-up should be recommended for these patients to decrease the nutritional impact on global health. More homogeneous studies must be conducted to reach robust conclusions regarding the best type of nutritional intervention for these patients.

Indexed as

Nutritional StatusPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentAntineoplastic AgentsChildChild, PreschoolFemaleHumansInfantMaleMalnutritionNutrition AssessmentAntineoplastic Agentschildrenleukaemianutritional statusnutrition assessmentsystematic reviewtreatment

Identifiers

PMID39683512
PMCPMC11643874

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.