Evidence mapPaperPMID 39683592Full record

Trial reportNutrients2024

Effects of

Francesco Di Pierro, Davide Sisti, Marco Rocchi, Annalisa Belli, Alexander Bertuccioli, Massimiliano Cazzaniga, Chiara Maria Palazzi, Maria Laura Tanda, Nicola Zerbinati

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Unraveling the Effects ofInternational journal of molecular sciences · 2025
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco Di PierroDepartment of Medicine and Technological Innovation, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-6654-8675
Davide SistiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-7925-7495
Marco RocchiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-0056-5795
Annalisa BelliDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.
Alexander BertuccioliMicrobiota International Clinical Society, 10123 Torino, Italy.ORCID 0000-0002-3922-9115
Massimiliano CazzanigaMicrobiota International Clinical Society, 10123 Torino, Italy.
Chiara Maria PalazziMicrobiota International Clinical Society, 10123 Torino, Italy.
Maria Laura TandaDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-7551-1751
Nicola ZerbinatiDepartment of Medicine and Technological Innovation, University of Insubria, 21100 Varese, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsas nutraceuticals and botanicals could be an alternative option to prescription medications for alleviating symptoms of mild anxiety and insomnia, we have verified in a prospective, double-blind, placebo-controlled, and cross-over study the supporting role on sleep quality played by a

resultsresults showed a significant reduction in the ISI score in the treated group, with an average of 6.8 ± 4.1 compared to 9.7 ± 3.7 in the placebo group, indicating a significant reduction of 2.9 points (

conclusionsthese findings suggest that MOP may represent a natural and safe alternative to traditional pharmacological treatments for insomnia.

Indexed as

Cross-Over StudiesDietary SupplementsMelissaPlant ExtractsSleep QualityAdultAnxietyBiological AvailabilityCinnamatesDepsidesDouble-Blind MethodFemaleHumansMaleMiddle AgedProspective StudiesCinnamatesDepsidesPlant ExtractsRosmarinic AcidGABA-Thydroxycinnamic acidsoral bioavailabilityrosmarinic acid

Identifiers

PMID39683592
PMCPMC11644815

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.