Evidence mapPaperPMID 39683608Full record

ArticleNutrients2024

Study Protocol for a Randomized Controlled Trial Investigating the Effects of the Daily Consumption of Ruminant Milk on Digestive Comfort and Nutrition in Older Women: The YUMMI Study.

Shien Ping Ong, Jody C Miller, Warren C McNabb, Richard B Gearry, Lara M Ware, Jane A Mullaney, Karl Fraser, Joanne Hort, Simone B Bayer, Chris M A Frampton and 1 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shien Ping OngDepartment of Human Nutrition, University of Otago, Dunedin 9016, New Zealand.ORCID 0000-0002-6121-2790
Jody C MillerDepartment of Human Nutrition, University of Otago, Dunedin 9016, New Zealand.
Warren C McNabbRiddet Institute, Massey University, Palmerston North 4410, New Zealand.ORCID 0000-0003-2514-6551
Richard B GearryHigh-Value Nutrition National Science Challenge, Liggins Institute, Auckland 1023, New Zealand.
Lara M WareDepartment of Human Nutrition, University of Otago, Dunedin 9016, New Zealand.
Jane A MullaneyRiddet Institute, Massey University, Palmerston North 4410, New Zealand.ORCID 0000-0002-4910-7605
Karl FraserRiddet Institute, Massey University, Palmerston North 4410, New Zealand.ORCID 0000-0002-1136-4024
Joanne HortRiddet Institute, Massey University, Palmerston North 4410, New Zealand.ORCID 0000-0001-8609-4543
Simone B BayerHigh-Value Nutrition National Science Challenge, Liggins Institute, Auckland 1023, New Zealand.ORCID 0000-0002-5880-2095
Chris M A FramptonDepartment of Medicine, University of Otago, Christchurch 8011, New Zealand.
Nicole C RoyDepartment of Human Nutrition, University of Otago, Dunedin 9016, New Zealand.ORCID 0000-0002-6744-9705

Funding

High-Value Nutrition National Science Challenge funded by the New Zealand Ministry of Business, Innovation and Employment (MBIE) UOAX1902
6 · The paper itself

Abstract

backgroundAge-related changes can lead to dietary insufficiency in older adults. The inclusion of high-quality, nutrient-dense foods such as ruminant milks can significantly improve health outcomes. However, many older adults worldwide do not meet daily milk intake recommendations because of digestive discomfort and health concerns. Ovine and caprine milks are increasingly popular for their perceived digestive and nutritional benefits. While preclinical studies suggest differences in milk digestion, human studies investigating acute postprandial responses remain inconclusive, and the impacts of sustained milk consumption remain uncertain.

objectivesHence, we present a randomized controlled trial investigating how the sustained consumption of bovine, caprine, or ovine milk influences digestion, nutrition, and metabolism in older women.

methodsA total of 165 healthy older women were randomized to receive bovine, caprine, or ovine milk, or no milk, twice daily for 12 weeks. The primary outcome is the impact of milk consumption on digestive comfort assessed via the Gastrointestinal Syndrome Rating Scale (GSRS). Secondary outcomes include changes in nutrient intake, plasma amino acid and lipid appearance, bowel habits, the gut microbiota, cardiometabolic health, physical function, physical activity, sleep, mood, sensory perception, and emotional response.

conclusionsThe findings could inform dietary recommendations for older women and facilitate the development of targeted functional food products.

Indexed as

DigestionMilkAgedAnimalsCattleDietFemaleGoatsHumansMiddle AgedNutritional StatusRandomized Controlled Trials as TopicSheepdietary interventiondigestive comfortolder womenruminant milkstudy protocol

Identifiers

PMID39683608
PMCPMC11644153

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.