Synthesis of Antimicrobial Norlabdane Compounds with Rearranged Cycle B and Molecular Docking Studies.

Alexandru Ciocarlan, Lidia Lungu, Sergiu Shova, Nicoleta Vornicu, Natalia Bolocan, Veaceslav Kulcitki, Aculina Aricu

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Phytochemical Profiling and Antibacterial Activity of Moroccan Monofloral Honeys Against Multidrug-Resistant Uropathogens: In Vitro, ADMET, Molecular Docking, and Molecular Dynamics Approaches.Food science & nutrition · 2026
Article
Sequential soxhlet fractionation ofFrontiers in chemistry · 2026
Article
Elucidating the isorhamnetin-3-O-glucoside-iNOS interaction via molecular dynamics and Hirshfeld surface analyses.PloS one · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandru CiocarlanInstitute of Chemistry, Moldova State University, 2028 Chisinau, Moldova.

Lidia LunguInstitute of Chemistry, Moldova State University, 2028 Chisinau, Moldova.

Sergiu Shova"P. Poni" Institute of Macromolecular Chemistry, 700487 Iasi, Romania.ORCID 0000-0002-1222-4373

Nicoleta VornicuMetropolitan Center of Research T.A.B.O.R. (Tehnologie Arta Biserica Ortodoxa Romana), 700066 Iasi, Romania.ORCID 0000-0002-4025-2582

Natalia BolocanInstitute of Chemistry, Moldova State University, 2028 Chisinau, Moldova.

Veaceslav KulcitkiInstitute of Chemistry, Moldova State University, 2028 Chisinau, Moldova.ORCID 0000-0002-9363-1615

Aculina AricuInstitute of Chemistry, Moldova State University, 2028 Chisinau, Moldova.

Funding

State University of Moldova 010601

6 · The paper itself

Abstract

The synthesis of tetra- and pentanorlabdane compounds with rearranged cycle B based on commercially available (+)-sclareolide is reported. Desired compounds were prepared from intermediate ketones via Baeyer-Villiger oxidation. The structures of synthesized compounds were confirmed by spectral IR, 1D (

Indexed as

Microbial Sensitivity TestsMolecular Docking SimulationAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsDNA GyraseEscherichia coliMolecular StructureAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsDNA Gyrase7-oxo-12,13,14,15,16-pentanorlabd-8-eneantimicrobial activityBaeyer-Villiger oxidationDFTmethyl 7-oxo-13,14,15,16-tetranorlabd-8-en-12-oate(+)-sclareolide

Identifiers

PMID39683873

DOI10.3390/molecules29235714

PMCPMC11643738

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.