Evidence map›Paper›PMID 39684564›Full record

Trial reportInternational journal of molecular sciences2024

Effect of Silibinin on Human Pancreatic Lipase Inhibition and Gut Microbiota in Healthy Volunteers: A Randomized Controlled Trial.

Cristina Ponce Martínez, Elena Murcia García, Horacio Pérez Sánchez, Fermín I Milagro, José I Riezu-Boj, Bruno Ramos Molina, María Gómez Gallego, Salvador Zamora, Rubén Cañavate Cutillas, Juan José Hernández Morante

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cristina Ponce MartínezUnidad de Investigación de Trastornos de la Alimentación, Facultad de Enfermería, Universidad Católica de Murcia, Campus de Guadalupe, Avda. de Los Jerónimos, s/n, 30107 Murcia, Spain.
Elena Murcia GarcíaUnidad de Investigación de Trastornos de la Alimentación, Facultad de Enfermería, Universidad Católica de Murcia, Campus de Guadalupe, Avda. de Los Jerónimos, s/n, 30107 Murcia, Spain.ORCID 0000-0002-9679-3871
Horacio Pérez SánchezBioinformatics and High Performance Computing Group, Universidad Católica de Murcia, Campus de Guadalupe, Avda. de Los Jerónimos, s/n, 30107 Murcia, Spain.ORCID 0000-0003-4468-7898
Fermín I MilagroDepartment of Nutrition, Food Sciences and Physiology, Center for Nutrition Research, Universidad de Navarra, C/Irunlarrea, 1, 31008 Pamplona, Spain.ORCID 0000-0002-3228-9916
José I Riezu-BojNavarra Institute for Health Research (IdiSNA), C/Irunlarrea, 3, 31008 Pamplona, Spain.ORCID 0000-0002-1885-8457
Bruno Ramos MolinaObesity, Diabetes and Metabolism Laboratory, Biomedical Research Institute of Murcia (IMIB), 30120 Murcia, Spain.ORCID 0000-0001-6804-5449
María Gómez GallegoFacultad de Ciencias Sociosanitarias, Campus de Lorca, Av. de las Fuerzas Armadas, 0, Lorca, 30800 Murcia, Spain.ORCID 0000-0002-1650-7207
Salvador ZamoraDepartamento de Fisiología, Facultad de Biología, Universidad de Murcia, C/Campus Universitario, 5, 30100 Murcia, Spain.
Rubén Cañavate CutillasUnidad de Investigación de Trastornos de la Alimentación, Facultad de Enfermería, Universidad Católica de Murcia, Campus de Guadalupe, Avda. de Los Jerónimos, s/n, 30107 Murcia, Spain.
Juan José Hernández MoranteUnidad de Investigación de Trastornos de la Alimentación, Facultad de Enfermería, Universidad Católica de Murcia, Campus de Guadalupe, Avda. de Los Jerónimos, s/n, 30107 Murcia, Spain.ORCID 0000-0001-9255-4630

Funding

CIBEROBN CB12/03/30002Institute of Health Carlos III CP19/00098SENECA Foundation #21646/PDC/21
6 · The paper itself

Abstract

Thistle (

Indexed as

Gastrointestinal MicrobiomeLipaseSilybinAdultAnti-Obesity AgentsFecesFemaleHealthy VolunteersHumansMaleMiddle AgedOrlistatPancreasSilymarinAnti-Obesity AgentsLipaseOrlistatPNLIP protein, humanSilybinSilymarinmicrobiotaobesitypancreatic lipasesilibininthistle extract

Identifiers

PMID39684564
PMCPMC11640983

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.