Evidence map›Paper›PMID 39684616›Full record

ArticleInternational journal of molecular sciences2024

Targeting Oxidative Stress and Inflammation in the Eye: Insights from a New Model of Experimental Autoimmune Uveitis.

Dmitry V Chistyakov, Veronika V Tiulina, Olga S Gancharova, Viktoriia E Baksheeva, Sergei V Goriainov, Natalia G Shebardina, Vasily A Ivlev, Sergey V Komarov, Marina P Shevelyova, Natalia K Tikhomirova and 8 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Dmitry V ChistyakovBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.ORCID 0000-0003-0137-8585
Veronika V TiulinaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Olga S GancharovaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Viktoriia E BaksheevaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Sergei V GoriainovPharmacy Resource Center, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.ORCID 0000-0002-7625-9110
Natalia G ShebardinaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Vasily A IvlevPharmacy Resource Center, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.ORCID 0000-0001-9664-9506
Sergey V KomarovSkryabin Moscow State Academy of Veterinary Medicine and Biotechnology, 109472 Moscow, Russia.
Marina P ShevelyovaInstitute for Biological Instrumentation, Russian Academy of Sciences, 142292 Pushchino, Russia.ORCID 0009-0004-7638-5143
Natalia K TikhomirovaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Pavel P PhilippovBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Vasiliy G Vasil'evPharmacy Resource Center, Peoples' Friendship University of Russia (RUDN University), 117198 Moscow, Russia.ORCID 0000-0002-7764-693X
Marina G SergeevaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Sergei E PermyakovInstitute for Biological Instrumentation, Russian Academy of Sciences, 142292 Pushchino, Russia.ORCID 0000-0003-4086-3137
Elena N IomdinaHelmholtz National Medical Research Center of Eye Diseases, 105062 Moscow, Russia.ORCID 0000-0001-8143-3606
Philipp O TsvetkovCNRS, UMR 7051, INP, Inst Neurophysiopathol, Faculté des Sciences Médicales et Paramédicales, Aix Marseille Univ, 13005 Marseille, France.ORCID 0000-0002-8622-8836
Ivan I SeninBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.
Evgeni Yu ZerniiBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.ORCID 0000-0002-3013-7863

Funding

Russian Science Foundation 16-15-00255Russian Science Foundation 24-15-00171
6 · The paper itself

Abstract

Autoimmune uveitis is a relapsing blind-causing ocular condition with complex pathogenesis that is not completely understood. There is a high demand for accurate animal models of experimental autoimmune uveitis (EAU) suitable for elucidating the molecular mechanisms of the disease and testing new therapeutic approaches. Here, we demonstrated that photoreceptor Ca

Indexed as

Autoimmune DiseasesDisease Models, AnimalOxidative StressUveitisAnimalsInflammationRabbitsRetinaaqueous humor lipidomicsaqueous humor metabolomicsascorbic acidexperimental autoimmune uveitismitochondria-targeted antioxidantoxidative stressoxylipinspolyunsaturated fatty acidsrecoverinSkQ1

Identifiers

PMID39684616
PMCPMC11641703

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.