Evidence map›Paper›PMID 39684625›Full record

ArticleInternational journal of molecular sciences2024

Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration.

Sheila Caño-Carrillo, Carlos Garcia-Padilla, Amelia E Aranega, Estefania Lozano-Velasco, Diego Franco

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sheila Caño-CarrilloCardiovascular Development Group, Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain.ORCID 0000-0002-3746-877X
Carlos Garcia-PadillaCardiovascular Development Group, Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain.ORCID 0000-0003-2061-3157
Amelia E AranegaCardiovascular Development Group, Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain.ORCID 0000-0002-0046-9410
Estefania Lozano-VelascoCardiovascular Development Group, Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain.ORCID 0000-0002-5615-2754
Diego FrancoCardiovascular Development Group, Department of Experimental Biology, University of Jaen, 23071 Jaen, Spain.ORCID 0000-0002-5669-7164

Funding

Consejería de Transformación Económica, Industria, Conocimiento y Universidades, Junta de Andalucía ProyExcel_00409Ministerio de Ciencia e Innovación, Gobierno de España PID2022-138163OB-C32
6 · The paper itself

Abstract

Cardiac development is a complex developmental process. The early cardiac straight tube is composed of an external myocardial layer and an internal endocardial lining. Soon after rightward looping, the embryonic heart becomes externally covered by a new epithelial lining, the embryonic epicardium. A subset of these embryonic epicardial cells migrate and colonize the embryonic myocardium, contributing to the formation of distinct cell types. In recent years, our understanding of the molecular mechanisms that govern proepicardium and embryonic epicardium formation has greatly increased. We have recently witnessed the discovery of a novel layer of complexity governing gene regulation with the discovery of non-coding RNAs. Our laboratory recently identified three distinct lncRNAs, adjacent to the

Indexed as

Cell MovementGene Expression Regulation, DevelopmentalMEF2 Transcription FactorsPericardiumRNA, Long NoncodingAnimalsChick EmbryoChickensHomeobox Protein Nkx-2.5MiceHomeobox Protein Nkx-2.5Mef2c protein, mouseMEF2 Transcription FactorsRNA, Long Noncodingcell migrationcytoskeletal remodelingepicardial celllncRNAs

Identifiers

PMID39684625
PMCPMC11640978

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.