Evidence map›Paper›PMID 39684693›Full record

ArticleInternational journal of molecular sciences2024

Evaluation of In Vitro Biological Activity of Flavanone/Chromanone Derivatives: Molecular Analysis of Anticancer Mechanisms in Colorectal Cancer.

Pawel Hikisz, Piotr Wawrzyniak, Angelika A Adamus-Grabicka, Damian Jacenik, Elzbieta Budzisz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pawel HikiszDepartment of Oncobiology and Epigenetics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Piotr WawrzyniakDepartment of Molecular Biology of Cancer, Medical University of Lodz, 6/8 Mazowiecka Street, 92-215 Lodz, Poland.ORCID 0009-0000-6225-4354
Angelika A Adamus-GrabickaDepartment of Bioinorganic Chemistry, Faculty of Pharmacy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.ORCID 0000-0003-0119-599X
Damian JacenikDepartment of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, ul. Pomorska 141/143, 90-236 Lodz, Poland.ORCID 0000-0003-4563-2303
Elzbieta BudziszDepartment of the Chemistry of Cosmetic Raw Materials, Medical University of Lodz, 90-151 Lodz, Poland.ORCID 0000-0001-9949-8723

Funding

National Science Center 2023/07/X/NZ3/01404
6 · The paper itself

Abstract

The primary objective of this study was to evaluate the anticancer activity of six flavanone/chromanone derivatives:

Indexed as

Antineoplastic AgentsApoptosisAutophagyCell ProliferationColorectal NeoplasmsDNA DamageFlavanonesReactive Oxygen SpeciesCell Line, TumorGlutathioneHumansOxidative StressAntineoplastic AgentsflavanoneFlavanonesGlutathioneReactive Oxygen Speciesanticancer propertiesapoptosischromanonecolon cancerflavanoneflavonoid derivativesgenotoxicityreactive oxygen speciesstructure–activity relationship

Identifiers

PMID39684693
PMCPMC11641365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.