Evidence map›Paper›PMID 39684791›Full record

ArticleInternational journal of molecular sciences2024

Activation of Bradykinin B

Ying Lu, Yishan Gu, Anthony S L Chan, Ying Yung, Yung H Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying LuDivision of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Yishan GuDivision of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Anthony S L ChanDivision of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Ying YungDivision of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Yung H WongDivision of Life Science and the Biotechnology Research Institute, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.ORCID 0000-0002-0123-7697

Funding

Innovation and Technology Commission of Hong Kong ITCPD/17-9National Key Basic Research Program of China 2013CB530900Research Grants Council of Hong Kong 16102018University Grants Committee of Hong Kong AoE/M-604/16
6 · The paper itself

Abstract

Communications between different cell types within a tissue are often critical for the proper functioning of an organ. In the central nervous system, interactions among neurons and glial cells are known to modulate neurotransmission, energy metabolism, extracellular ion homeostasis, and neuroprotection. Here we showed that bradykinin, a proinflammatory neuropeptide, can be detected by astrocytes, resulting in the secretion of cytokines that act on neurons. In astrocytic cell lines and primary astrocytes, bradykinin and several other ligands acting on G

Indexed as

AstrocytesAutocrine CommunicationBradykininLeukemia Inhibitory FactorParacrine CommunicationReceptor, Bradykinin B2STAT3 Transcription FactorAnimalsCalciumCells, CulturedCulture Media, ConditionedHumansInterleukin-6MiceNeuronsRatsBradykininCalciumCulture Media, ConditionedInterleukin-6Leukemia Inhibitory FactorReceptor, Bradykinin B2STAT3 Transcription Factorastrocytesbradykininleukemia inhibitory factorreceptorsignaling

Identifiers

PMID39684791
PMCPMC11642044

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.