Evidence map›Paper›PMID 39684850›Full record

ReviewInternational journal of molecular sciences2024

Evasion of the Antiviral Innate Immunity by PRV.

Chenlong Wang, Longxi Li, Xinyu Zhai, Hongtao Chang, Huimin Liu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Therapeutic potential ofFrontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chenlong WangCollege of Life Sciences, Henan Agricultural University, Zhengzhou 450046, China.
Longxi LiCollege of Life Sciences, Henan Agricultural University, Zhengzhou 450046, China.
Xinyu ZhaiCollege of Life Sciences, Henan Agricultural University, Zhengzhou 450046, China.
Hongtao ChangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Huimin LiuCollege of Life Sciences, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0002-2519-3799

Funding

Program for young backbone teachers in Universities of Henan Province 2021GGJS034Science and Technology Program of Henan Province 242102111027
6 · The paper itself

Abstract

Pseudorabies virus (PRV) establishes persistent latent infections by effectively evading the host's antiviral innate immune response. PRV has developed sophisticated strategies to bypass immune surveillance through coevolution with its host. Currently, no effective vaccine exists to prevent or treat infections caused by emerging PRV variants, and the interactions between PRV and the host's innate immune defenses remain incompletely understood. Nevertheless, ongoing research is uncovering insights that may lead to novel treatments and preventive approaches for herpesvirus-related diseases. This review summarizes recent advances in understanding how PRV disrupts key adaptors in immune signaling pathways to evade antiviral immunity. Additionally, we explored the intrinsic cellular defenses that play crucial roles in combating viral invasion. A deeper understanding of the immune evasion strategies of PRV could inform the development of new therapeutic targets and vaccines.

Indexed as

Herpesvirus 1, SuidImmune EvasionImmunity, InnateAnimalsHost-Pathogen InteractionsHumansPseudorabiesSignal Transductionimmune evasioninnate immunityPRV

Identifiers

PMID39684850
PMCPMC11642419

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.