Evidence map›Paper›PMID 39687425›Full record

ArticleEClinicalMedicine2024

Risk of intraoperative hemorrhage during cesarean scar ectopic pregnancy surgery: development and validation of an interpretable machine learning prediction model.

Xinli Chen, Huan Zhang, Dongxia Guo, Siyuan Yang, Bao Liu, Yiping Hao, Qingqing Liu, Teng Zhang, Fanrong Meng, Longyun Sun and 6 more

Abstract read
In one paragraph

Article in EClinicalMedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Risk prediction of non-small cell lung cancer in patients with pulmonary nodules: a single-center cohort study based on six machine learning algorithms.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  3. Article
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  5. An explainable predictive machine learning model of oxaliplatin induced peripheral neuropathy based on clinical data: a retrospective single center.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  6. Article
  7. Surgical bleeding prediction using transformer: an application to laparoscopic cholecystectomy.International journal of computer assisted radiology and surgery · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xinli ChenDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Huan ZhangDezhou Maternal and Child Health Care Hospital, Dezhou, China.
Dongxia GuoLiao Cheng Dong Chang Fu District Maternal and Child Health Care Hospital, Liaocheng, China.
Siyuan YangDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Bao LiuChongqing Health Center for Women and Children, Chongqing, China.
Yiping HaoDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Qingqing LiuDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Teng ZhangDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Fanrong MengLiao Cheng Dong Chang Fu District Maternal and Child Health Care Hospital, Liaocheng, China.
Longyun SunDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Xinlin JiaoDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Wenjing ZhangDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Yanli BanDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.
Yugang ChiChongqing Health Center for Women and Children, Chongqing, China.
Guowei TaoDepartment of Ultrasound, Qilu Hospital of Shandong University, Jinan, China.
Baoxia CuiDepartment of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current models for predicting intraoperative hemorrhage in cesarean scar ectopic pregnancy (CSEP) are constrained by known risk factors and conventional statistical methods. Our objective is to develop an interpretable prediction model using machine learning (ML) techniques to assess the risk of intraoperative hemorrhage during CSEP in women, followed by external validation and clinical application. Methods: This multicenter retrospective study utilized electronic medical record (EMR) data from four tertiary medical institutions. The model was developed using data from 1680 patients with CSEP diagnosed and treated at Qilu Hospital of Shandong University, Chongqing Health Center for Women and Children, and Dezhou Maternal and Child Health Care Hospital between January 1, 2008, and December 31, 2023. External validation data were obtained from Liao Cheng Dong Chang Fu District Maternal and Child Health Care Hospital between January 1, 2021, and December 31, 2023. Random forest (RF), Lasso, Boruta, and Extreme Gradient Boosting (XGBoost) were employed to identify the most influential variables in the model development data set; the best variables were selected based on reaching the λ Findings: Setting λ Interpretation: The developed prediction model, deployed in the network application, is capable of forecasting the risk of intraoperative hemorrhage during CSEP. This tool can facilitate targeted preoperative assessment and clinical decision-making for clinicians. Prospective data should be utilized in future studies to further validate the extended applicability of the model. Funding: Natural Science Foundation of Shandong Province; Qilu Hospital of Shandong University.

Indexed as

Cesarean scar ectopic pregnancyInterpretable machine learningIntraoperative hemorrhagePrediction modelVisualization

Identifiers

PMID39687425
PMCPMC11646795

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.