Evidence map›Paper›PMID 39687741›Full record

ArticleFrontiers in genetics2024

Genetic surveillance shows spread of ACT resistance during period of malaria decline in Vietnam (2018-2020).

Johanna Helena Kattenberg, Mathijs Mutsaers, Van Hong Nguyen, Thi Hong Ngoc Nguyen, Arlette Umugwaneza, Maria Lara-Escandell, Xuan Xa Nguyen, Thi Huong Binh Nguyen, Anna Rosanas-Urgell

Abstract read
In one paragraph

Article in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Changing genetic profiles ofAntimicrobial agents and chemotherapy · 2026
    Article
  4. Article
  5. Saliva-based molecular diagnostics in oral squamous cell carcinoma (OSCC): a non-invasive frontier in oncology.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Johanna Helena KattenbergBiomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium.
Mathijs Mutsaers *Biomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium.
Van Hong Nguyen *Department of Clinical Research, National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam.
Thi Hong Ngoc NguyenDepartment of Molecular Biology, National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam.
Arlette UmugwanezaBiomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium.
Maria Lara-EscandellBiomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium.
Xuan Xa NguyenRegional Artemisinin Initiative, RAI project, National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam.
Thi Huong Binh NguyenDepartment of Clinical Research, National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam.
Anna Rosanas-UrgellBiomedical Sciences Department, Institute of Tropical Medicine, Antwerp, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Vietnam's goal to eliminate malaria by 2030 is challenged by the further spread of drug-resistant Methods: The custom targeted NGS amplicon sequencing assay, AmpliSeq Pf Vietnam v2, targeting drug resistance, population genetic- and other markers, was applied to detect genetic diversity and resistance profiles in samples from 8 provinces in Vietnam (n = 354), in a period of steep decline of incidence (2018-2020). Variants in 14 putative resistance genes, including Results: A concerning level of DHA-PPQ resistance was detected. The C580Y mutation in Discussion: In conclusion, examining a broad panel of full-length resistance genes and SNPs provided high-resolution insights into genetic diversity and resistance evolution in Vietnam, offering valuable information to inform local treatment and intervention strategies.

Indexed as

artemisinin resistancedrug resistancemalaria molecular surveillancenext-generation sequencingpiperaquine resistancePlasmodium falciparumVietnam

Identifiers

PMID39687741
PMCPMC11646998

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.