Evidence map›Paper›PMID 39688713›Full record

ArticleParasitology research2024

Characterization and expression analysis of heat shock proteins HfHspc1 and HfHspc4 in Haemaphysalis flava ticks.

Yong Li, Lan-Lan Wang, Li-Li Feng, De-Yong Duan, Darko Mihaljica, Tian-Yin Cheng

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Article in Parasitology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yong Li *Research Center for Parasites & Vectors, College of Veterinary Medicine, Hunan Agricultural University, Hunan Province 410128, Changsha, China.
Lan-Lan Wang *Research Center for Parasites & Vectors, College of Veterinary Medicine, Hunan Agricultural University, Hunan Province 410128, Changsha, China.
Li-Li FengResearch Center for Parasites & Vectors, College of Veterinary Medicine, Hunan Agricultural University, Hunan Province 410128, Changsha, China.
De-Yong DuanResearch Center for Parasites & Vectors, College of Veterinary Medicine, Hunan Agricultural University, Hunan Province 410128, Changsha, China.
Darko MihaljicaGroup for Medical Entomology, Centre of Excellence for Food- and Vector-Borne Zoonoses, Institute for Medical Research, National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia. darko.mihaljica@imi.bg.ac.rs.
Tian-Yin ChengResearch Center for Parasites & Vectors, College of Veterinary Medicine, Hunan Agricultural University, Hunan Province 410128, Changsha, China. hn5368@163.com.

Funding

National Natural Science Foundation of China No. 31372431Natural Science Foundation of Hunan, Changsha, China 2023JJ30287
6 · The paper itself

Abstract

In this study, the cDNAs of heat shock cognate 90 protein 1 (HfHspc1) and heat shock cognate 90 protein 4 (HfHspc4) from Haemaphysalis flava (Acari: Ixodidae) were obtained using the rapid amplification of cDNA ends (RACE) approach, and the expression patterns of HfHspc1 and HfHspc4 in different developmental stages, engorgement stages and tick organs were analyzed by qPCR. The full length of HfHspc1 was 2411 bp, and its open reading frame (ORF) was 2196 bp, encoding a protein of 732 aa, containing five HSPC family signatures, with MEEVD motif at its extreme C-terminal. The full length of HfHspc4 was 2800 bp, and its ORF was 2364 bp, encoding a protein of 789 aa, containing a signal peptide and five family signatures, with HEEL motif at its extreme C-terminal. The expression of HfHspc1 and HfHspc4 was the highest in males, while it was significantly the highest in the ovaries of fully engorged females, potentially implying the roles of these proteins in the successful digestion of blood and development of eggs.

Indexed as

IxodidaeAmino Acid SequenceAnimalsArthropod ProteinsDNA, ComplementaryFemaleGene Expression ProfilingHeat-Shock ProteinsMaleMolecular Sequence DataPhylogenyReal-Time Polymerase Chain ReactionSequence Analysis, DNAArthropod ProteinsDNA, ComplementaryHeat-Shock ProteinsHaemaphysalis flavaHeat shock proteinsHfHspc1HfHspc4

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.