Evidence map›Paper›PMID 39688715›Full record

ArticlePlant cell reports2024

DET1 modulates ATAF1-repressed thermosensory elongation through ubiquitination in Arabidopsis.

Shuai Yuan, Yan Li, Yayi Li, Juan Wei, Min Liu, Feng Yang, Xiuhong Yao

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Article in Plant cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shuai YuanSolid-State Fermentation Resource Utilization Key Laboratory of Sichuan Province, Department of Agriculture Forestry and Food Engineering, Yibin University, Yibin, China.
Yan LiSolid-State Fermentation Resource Utilization Key Laboratory of Sichuan Province, Department of Agriculture Forestry and Food Engineering, Yibin University, Yibin, China.
Yayi LiSolid-State Fermentation Resource Utilization Key Laboratory of Sichuan Province, Department of Agriculture Forestry and Food Engineering, Yibin University, Yibin, China.
Juan WeiSolid-State Fermentation Resource Utilization Key Laboratory of Sichuan Province, Department of Agriculture Forestry and Food Engineering, Yibin University, Yibin, China.
Min LiuSolid-State Fermentation Resource Utilization Key Laboratory of Sichuan Province, Department of Agriculture Forestry and Food Engineering, Yibin University, Yibin, China.
Feng YangRice and Sorghum Research Institute, Sichuan Academy of Agricultural Sciences (Deyang Branch, Sichuan Academy of Agricultural Sciences), Deyang, 618099, China. yangfeng@scsaas.cn.
Xiuhong YaoSolid-State Fermentation Resource Utilization Key Laboratory of Sichuan Province, Department of Agriculture Forestry and Food Engineering, Yibin University, Yibin, China. yaoxiuhong@yibinu.edu.cn.ORCID http://orcid.org/0000-0002-4047-4310

Funding

National Natural Science Foundation of China U22A20494Solid-State Fermentation Resource Utilization Key Laboratory of Sichuan Province 2023GTZD03the Doctoral Research Launch Project of Sichuan Academy of Agricultural Sciences NKYRCZX2024036the Project of Sichuan Province Engineering Technology Research Center of Vegetables 2023PZSC0303
6 · The paper itself

Abstract

key messageThe Arabidopsis transcription factor ATAF1 negatively regulates thermomorphogenesis by inhibiting the expression of key genes involved in thermoresponsive elongation. DET1-mediated ubiquitination promotes ATAF1 degradation. In response to warmer, non-stressful average temperatures, plants have evolved an adaptive morphologic response called thermomorphogenesis to increase their fitness. This adaptive morphologic development is regulated by transcription factors (TFs) that control the expression of heat-induced genes that gate thermoresponsive growth. No apical meristem (NAM), Arabidopsis thaliana-activating factor 1/2 (ATAF1/2), and cup-shaped cotyledon 2 (CUC2) (collectively known as NAC) TFs regulate morphogenesis and respond to temperature stress, but whether they regulate thermomorphogenesis remains largely unknown. Here, we identified ATAF1 as a negative regulator of thermomorphogenesis and revealed that the E3-ligase component de-etiolated 1 (DET1) mediated ATAF1 ubiquitination and degradation. Our results revealed that ATAF1 negatively regulates warm temperature-induced hypocotyl elongation and inhibits the expression of thermoresponsive genes. Moreover, ATAF1 directly targeted and repressed the expression of YUCCA 8 (YUC8) and phytochrome interacting factor 4 (PIF4), two key regulators involved in elongation. At the post-translational level, elevated ambient temperatures negatively modulated the stability of ATAF1 by inducing the DET1-mediated ubiquitination pathway. Our results demonstrated the presence of a DET1-ATAF1-PIF4/YUC8 control module for thermomorphogenesis in plants, which may increase fitness by fine-tuning thermoresponsive gene expression under warm temperatures.

Indexed as

ArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantUbiquitinationHypocotylIntracellular Signaling Peptides and ProteinsNuclear ProteinsPlants, Genetically ModifiedTemperatureTranscription FactorsArabidopsis ProteinsDET1 protein, ArabidopsisIntracellular Signaling Peptides and ProteinsNuclear ProteinsTranscription FactorsATAF1DET1ThermomorphogenesisTranscriptional regulationUbiquitination

Identifiers

PMID39688715

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.