Evidence mapPaperPMID 39690739Full record

ArticlePlant communications2025

Cropformer: An interpretable deep learning framework for crop genomic prediction.

Hao Wang, Shen Yan, Wenxi Wang, Yongming Chen, Jingpeng Hong, Qiang He, Xianmin Diao, Yunan Lin, Yanqing Chen, Yongsheng Cao and 2 more

Abstract read
In one paragraph

Article in Plant communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hao WangState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Shen YanState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Wenxi WangFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), and Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing 100193, China.
Yongming ChenFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), and Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing 100193, China; State Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Shandong 261325, China.
Jingpeng HongCollege of Information and Management Science, Henan Agricultural University, Zhengzhou 450002, China.
Qiang HeState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Xianmin DiaoState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Yunan LinSchool of Engineering and Design, Technical University Munich, 85521 Munich, Germany.
Yanqing ChenState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Yongsheng CaoState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: caoyongsheng@caas.cn.
Weilong GuoFrontiers Science Center for Molecular Design Breeding, Key Laboratory of Crop Heterosis and Utilization (MOE), and Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing 100193, China. Electronic address: guoweilong@cau.edu.cn.
Wei FangState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: fangwei@caas.cn.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

Machine learning and deep learning are extensively employed in genomic selection (GS) to expedite the identification of superior genotypes and accelerate breeding cycles. However, a significant challenge with current data-driven deep learning models in GS lies in their low robustness and poor interpretability. To address these challenges, we developed Cropformer, a deep learning framework for predicting crop phenotypes and exploring downstream tasks. This framework combines convolutional neural networks with multiple self-attention mechanisms to improve accuracy. The ability of Cropformer to predict complex phenotypic traits was extensively evaluated on more than 20 traits across five major crops: maize, rice, wheat, foxtail millet, and tomato. Evaluation results show that Cropformer outperforms other GS methods in both precision and robustness, achieving up to a 7.5% improvement in prediction accuracy compared to the runner-up model. Additionally, Cropformer enhances the analysis and mining of genes associated with traits. We identified numerous single nucleotide polymorphisms (SNPs) with potential effects on maize phenotypic traits and revealed key genetic variations underlying these differences. Cropformer represents a significant advancement in predictive performance and gene identification, providing a powerful general tool for improving genomic design in crop breeding. Cropformer is freely accessible at https://cgris.net/cropformer.

Indexed as

Crops, AgriculturalDeep LearningGenome, PlantGenomicsGenotypeOryzaPhenotypePlant BreedingPolymorphism, Single NucleotideSolanum lycopersicumTriticumZea maysdeep learninggenomic selectionmultiple self-attention mechanismsphenotypic prediction

Identifiers

PMID39690739
PMCPMC11956090

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.