Evidence map›Paper›PMID 39691708›Full record

ArticleFrontiers in immunology2024

A new perspective on macrophage-targeted drug research: the potential of

Zhiyi Zhao, Hongling Jia, Zhou Sun, Yumeng Li, Lingyun Liu

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhiyi ZhaoDepartment of Andrology, The First Hospital of Jilin University, Changchun, Jilin, China.
Hongling JiaThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Zhou Sun *Department of Urology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
Yumeng Li *The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Lingyun Liu *Department of Andrology, The First Hospital of Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Bladder cancer was recognized as one of the most common malignant tumors in the urinary system, and treatment options remained largely limited to conventional surgery, radiotherapy, and chemotherapy, which limited patient benefits. Methods: Researchers constructed an RNA transcriptome map of bladder cancer by integrating single-cell RNA sequencing and clinical data, identifying potential molecular targets for diagnosis and treatment. We also verified the antitumor activity of the target through in vitro experiment. Results: A distinct tumor cell subpopulation characterized by elevated Discussion: The findings suggested that patients with high

Indexed as

ImmunotherapyMacrophagesUrinary Bladder NeoplasmsCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansSignal TransductionTumor-Associated Macrophagesbladder cancerKDELR2macrophageS100A8TCs

Identifiers

PMID39691708
PMCPMC11649672

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.