Evidence map›Paper›PMID 39691946›Full record

ArticleAmerican journal of epidemiology2026

The Green Heart Project: objectives, design, and methods.

Aruni Bhatnagar, Rachel Keith, Ray Yeager, Daniel Riggs, Clara Sears, Brent Bucknum, Ted Smith, Daniel Fleischer, Chris Chandler, Kandi L Walker and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in American journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03670524 (Health, Environment and Action in Louisville), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03670524 narecruitingnot on this map

Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project

TypeinterventionalSponsorUniversity of LouisvilleRan2018 to 2028Enrolled835ConditionsCardiovascular Diseases, Metabolic HealthArmsGreenness as a therapeutic intervention
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Review
  8. Article
  9. Perceived Benefits of Nature in Diverse Populations.International journal of environmental research and public health · 2025
    Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Aruni BhatnagarChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0001-6818-0384
Rachel KeithChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0003-3877-0636
Ray YeagerChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0002-5897-1913
Daniel RiggsChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0002-3503-0600
Clara SearsChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0002-5421-4077
Brent BucknumHyphae Design Laboratory, 942 Clay Street, Oakland, CA 94607, United States.ORCID 0000-0002-3674-076X
Ted SmithChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0003-2804-4294
Daniel FleischerHyphae Design Laboratory, 942 Clay Street, Oakland, CA 94607, United States.ORCID 0000-0002-5026-9185
Chris ChandlerThe Nature Conservancy, North American Cities Network. 308 Central Ave, Pewee Valley, KY 40056, United States.ORCID 0009-0003-3864-9323
Kandi L WalkerChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0003-1719-588X
Joy L HartChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0003-3220-2638
Sanjay SrivastavaChristina Lee Brown Envirome Institute, 302 E Muhammad Ali Blvd, Louisville, KY 40202, United States.ORCID 0000-0002-1976-0398
Jay TurnerDepartment of Chemical Engineering, Washington University, One Brookings Drive, St. Louis, MO 63130, United States.ORCID 0000-0001-7787-6244
Shesh RaiBiostatistics and Informatics Shared Resource, University of Cincinnati Cancer Center, 231 Albert Sabin Way, Cincinnati, OH 45229, United States.ORCID 0000-0002-8377-353X

Funding

Superfund Training CoreP42ES023716 · NIEHS · UNIVERSITY OF LOUISVILLE · PI HEIN, DAVID W · 2017 to 2025
$18.1M
Urban Greenness and Cardiovascular HealthR01ES029846 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Aruni Bhatnagar · 2018 to 2026
$6.2M
NIEHS NIH HHS ES023716NIEHS NIH HHS ES030283NIEHS NIH HHS grants ES029846NIEHS NIH HHS P42 ES023716NIEHS NIH HHS R01 ES029846
6 · The paper itself

Abstract

The Green Heart Project is a controlled, community-based clinical trial to evaluate the effects of increasing greenery on community health. The study was initiated in 2018 in a low- to middle-income residential area of nearly 30 000 racially diverse residents in Louisville, KY. Community engagement was maintained throughout the project, with feedback integrated into its design and implementation. Based on land use, demographics, and greenness in the area, we designated 8 paired clusters of demographically and environmentally matched target (T) and adjacent control (C) areas (total of 16 clusters). Levels of ultrafine particles, ozone, and nitrogen oxides were measured in each cluster. In-person exams were conducted for 735 participants in wave 1 (2018-2019) and 545 participants in wave 2 (2021). Blood, urine, nail, and hair samples were collected to evaluate cardiovascular risk, inflammation, stress, and pollutant exposure. Demographic and psychosocial data were collected as well. Cardiovascular function was assessed by measuring arterial stiffness and flow-mediated dilation. After wave 2, more than 8000 mature, mostly evergreen, trees and shrubs were planted in the T clusters. After planting, data were collected during wave 3 (2022) from 561 participants. We plan to follow changes in area characteristics and participant health to evaluate the long-term impact of the greening intervention. Trial registration: ClinicalTrials.gov. Identifier: NCT03670524.

Indexed as

Cardiovascular DiseasesConservation of Natural ResourcesAdultAgedEnvironmental ExposureFemaleHumansMaleMiddle Agedair pollutioncardiovascularclimate resilienceenvironmental healthenvironmental interventiongreennessgreen spaceimplementation

Identifiers

PMID39691946
PMCPMC13148999

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.