Evidence mapPaperPMID 39692888Full record

ReviewDie Ophthalmologie2025

[MiHUBx: a digital progress hub for the use of intersectoral clinical data sets using the example of diabetic macular edema].

Gabriel Stolze, Vinodh Kakkassery, Danny Kowerko, Martin Bartos, Katja Hoffmann, Martin Sedlmayr, Katrin Engelmann

Abstract readEnglish AbstractReview
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In one paragraph

Review in Die Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriel StolzeKlinik für Augenheilkunde, Klinikum Chemnitz gGmbH, Flemmingstraße 2, 09116, Chemnitz, Deutschland. g.stolze@skc.de.ORCID http://orcid.org/0009-0006-9190-1139
Vinodh KakkasseryKlinik für Augenheilkunde, Klinikum Chemnitz gGmbH, Flemmingstraße 2, 09116, Chemnitz, Deutschland.
Danny KowerkoFakultät für Informatik, Juniorprofessur Media Computing, Technische Universität Chemnitz, Straße der Nationen 62, 09111, Chemnitz, Deutschland.
Martin BartosBereich Informatik, Klinikum Chemnitz gGmbH, Flemmingstraße 2, 09116, Chemnitz, Deutschland.
Katja HoffmannInstitut für Medizinische Informatik und Biometrie, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 4, 01307, Dresden, Deutschland.ORCID http://orcid.org/0000-0003-4765-0767
Martin SedlmayrInstitut für Medizinische Informatik und Biometrie, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 4, 01307, Dresden, Deutschland.ORCID http://orcid.org/0000-0002-9888-8460
Katrin EngelmannKlinik für Augenheilkunde, Klinikum Chemnitz gGmbH, Flemmingstraße 2, 09116, Chemnitz, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence-based treatment recommendations are helpful in the corresponding discipline-specific treatment but can hardly take data from real-world care into account. In order to make better use of this in everyday clinical practice, including with respect to predictive statements about disease development or treatment success, models with data from treatment must be developed in order to use them for the development of assistive artificial intelligence. GOAL: The aim of the Use Case 1 of the medical informatics hub in Saxony (MiHUBx) is the development of a model based on treatment and research data for a treatment algorithm supported by biomarkers and also the development of the necessary digital infrastructure. MATERIAL AND

methodsStep by step, the necessary partners in hospitals and practices will be brought together technically or through research questions within Use Case 1 "Ophthalmology meets Diabetology", a regional digital progress hub in health, the medical informatics hub in Saxony (MiHUBx ) of the nationwide medical informatics initiative (MII).

resultsBased on joint studies with diabetologists, robust serological and imaging biomarkers were selected that provide evidence of the development of diabetic macular edema (DME). In the future, these and other scientifically proven prognostic markers will be incorporated into a treatment algorithm that is supported by artificial intelligence (AI). For this purpose, model procedures are being developed together with medical informatics specialists. At the same time, a data integration center (DIZ) was established.

conclusionIn addition to the structured and technical combination of the previously disseminated and partially heterogeneous treatment data, the Use Case 1 defines the chances and hurdles for using such real-world data to develop artificial intelligence.

Indexed as

Datasets as TopicDiabetic RetinopathyIntersectoral CollaborationMacular EdemaMedical InformaticsAlgorithmsArtificial IntelligenceGermanyHumansArtificial intelligenceDigitalizationMachine learningOphthalmologyTreatment algorithm

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.