Evidence map›Paper›PMID 39694328›Full record

Trial reportEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists2025

Randomized Study Comparing Continuous Glucose Monitoring and Capillary Glucose Testing in Patients With Type 2 Diabetes After Hospital Discharge.

Guillermo E Umpierrez, Iris Castro-Revoredo, Bobak Moazzami, Irina Nayberg, Zohyra Zabala, Rodolfo J Galindo, Priyathama Vellanki, Limin Peng, David C Klonoff

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Understanding Glycemia in the Post Discharge Period Through Blinded Continuous Glucose Monitoring.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026
    Observational
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guillermo E UmpierrezDivision of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Iris Castro-RevoredoDivision of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia. Electronic address: icastro@emory.edu.
Bobak MoazzamiDivision of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Irina NaybergDiabetes Research Institute, Mills-Peninsula Medical Center, San Mateo, California.
Zohyra ZabalaDivision of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Rodolfo J GalindoDivision of Endocrinology, Diabetes and Metabolism, University of Miami Miller School of Medicine, Miami, Florida.
Priyathama VellankiDivision of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Limin PengEmory University Rollins School of Public Health, Atlanta, Georgia.
David C KlonoffDiabetes Research Institute, Mills-Peninsula Medical Center, San Mateo, California.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Developing statistical analysis and prediction tools for continuous glucose monitoring (CGM) use in hospitalized patients with diabetesR01DK136023 · NIDDK · EMORY UNIVERSITY · PI Limin Peng · 2024 to 2026
$1.1M
Use of Continuous Glucose Monitoring (CGM) in End-Stage Renal Disease(ESRD) Patients with Type 2 DiabetesK23DK123384 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALINDO, RODOLFO · 2020 to 2024
$934k
Pharmaco-epidemiology of diabetes in patients with end-stage kidney diseaseR03DK138255 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALINDO, RODOLFO · 2024 to 2025
$230k
NCATS NIH HHS UL1 TR002378NIDDK NIH HHS K23 DK123384NIDDK NIH HHS P30 DK111024NIDDK NIH HHS R01 DK136023NIDDK NIH HHS R03 DK138255
6 · The paper itself

Abstract

objectiveThe benefits of continuous glucose monitoring (CGM) in managing hyperglycemia in hospitalized patients with type 2 diabetes (T2D) have been documented in observation and intervention clinical studies. However, the benefits of CGMs after hospital discharge in improving the care of patients with T2D remain unknown.

methodsThis pilot randomized clinical trial aimed to compare the effectiveness and safety of using the FreeStyle Libre 2 CGM vs capillary point-of-care (POC) glucose testing (standard of care) in insulin-treated patients with T2D for up to 12 weeks after hospital discharge. We assessed safety (hypoglycemia), efficacy (mean daily glucose), and healthcare utilization (emergency room visits and hospital admissions) associated with the use of FreeStyle Libre 2 CGM compared to capillary POC testing following hospital discharge.

resultsAmong 100 participants (mean age 54.3 ± 10.7 years, HbA1c 10.46 ± 2.24%, median diabetes duration of 9.0 years, IQR 1.0, 42), there were no significant differences in baseline clinical characteristics between the groups at discharge. We observed a trend toward improved glycemic control in the CGM group, including increased time in range 70-180 mg/dl, reduced time above range > 180 and 250 mg/dl, and decreased hypoglycemia and insulin requirements after discharge compared to the POC group. There were no differences in emergency room visits or hospitalization between the study groups.

conclusionThe results of this pilot study indicate that the use of CGM leads to improved glycemic control, reduced hypoglycemia, and decreased glucose variability compared to POC glucose testing after hospital discharge.

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 2AdultAgedContinuous Glucose MonitoringFemaleHumansHypoglycemiaHypoglycemic AgentsInsulinMaleMiddle AgedPatient DischargePilot ProjectsPoint-of-Care TestingBlood GlucoseHypoglycemic AgentsInsulinalgorithmCGMhospital dischargehospital hyperglycemiatechnologytype 2 diabetes

Identifiers

PMID39694328
PMCPMC12233000

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.