Evidence map›Paper›PMID 39694474›Full record

ArticleACS applied materials & interfaces2025

Analysis of Tribological and Cytotoxicity Assays of a Biocompatible Mg-Zn-Ca-Pr Alloy.

Sabina Lesz, Julia Popis, Barbara Grzegorczyk, Aleksandra Drygała, Bartłomiej Hrapkowicz, Wojciech Pakieła, Dariusz Ozimina, Julia Lisoń-Kubica, Klaudiusz Gołombek, Dariusz Garbiec and 1 more

Abstract read
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Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sabina LeszDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0002-2703-2059
Julia PopisDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0002-8773-5645
Barbara GrzegorczykDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0003-2813-7853
Aleksandra DrygałaDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0002-3443-6537
Bartłomiej HrapkowiczDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.
Wojciech PakiełaDepartment of Engineering Materials and Biomaterials, Faculty of Mechanical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.
Dariusz OziminaFaculty of Mechatronics and Mechanical Engineering, Kielce University of Technology, 25-314 Kielce, Poland.
Julia Lisoń-KubicaDepartment of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, 41-800 Zabrze, Poland.
Klaudiusz GołombekMaterials Research Laboratory, Faculty of Mechanical Engineering, Silesian University of Technology, 44-100 Gliwice, Poland.
Dariusz GarbiecŁukasiewicz Research Network - Poznań Institute of Technology, 61-755 Poznań, Poland.
Marcin BasiagaDepartment of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, 41-800 Zabrze, Poland.ORCID 0000-0001-5978-3861

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work covers a Mg-Zn-Ca-Pr alloy fabricated by a novel method of mechanical alloying and spark plasma sintering (SPS). Currently, magnesium alloys used as biomaterials are mostly commercial alloys without consideration of cytotoxicity from the perspective of biosafety. So far, the tribological and cytotoxic properties of Mg-Zn-Ca-Pr alloys have not been investigated. Hence, in the article, the tribological properties, considering wear rate, wear resistance, coefficient of friction, and the roughness of the sintered Mg-Zn-Ca-Pr alloy, are investigated. Cytotoxicity assays have also been carried out. The ball-on-a-disc method is used in the tribological test. Samples before sintering by the SPS method are milled at varying times of 13, 20, and 70 h. Results show that increasing the milling time affects tribology and cytotoxic tests. The longer the milling time, the lower the cell survival rate. The conducted tests reveal cell survival of 90, 82, and 61% for 13, 20, and 70 h, respectively. A reduction of cell viability by over 30% is considered a cytotoxic effect, which was observed only in the 70 h milling-time samples.

Indexed as

AlloysBiocompatible MaterialsCell SurvivalMagnesiumMaterials TestingZincAnimalsCalciumCell LineHumansMiceAlloysBiocompatible MaterialsCalciumMagnesiumZinccytotoxicity assaysmechanical alloyingMg-based alloyspark plasma sinteringwear resistance

Identifiers

PMID39694474
PMCPMC11783510

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.