Evidence mapPaperPMID 39694533Full record

ArticleRenal failure2025

The correlation between protein energy wasting and the incidence of main adverse cardiovascular events in adult maintenance hemodialysis patients: a single-center retrospective cohort study.

Xiaoyan Ma, Danying Yan, Canxin Zhou, Yingfeng Shi, Yi Wang, Jinqing Li, Qin Zhong, Xialin Li, Yan Hu, Weiwei Liang and 7 more

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Xiaoyan MaDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Danying YanDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Canxin ZhouDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yingfeng ShiDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yi WangDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Jinqing LiDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Qin ZhongDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Xialin LiDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yan HuDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Weiwei LiangDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Daofang JiangDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yishu WangDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Ting ZhangDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Yilin RuanDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Shasha ZhangDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Shougang ZhuangDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Na LiuDepartment of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProtein energy wasting (PEW) is prevalent in adult maintenance hemodialysis (MHD) patients. Concurrently, cardiovascular diseases (CVD) remain a leading cause of mortality in MHD patients. However, the relationship between PEW and CVD in MHD patients remains unclear.

methodsWe conducted a retrospective cohort study at Shanghai East Hospital. According to the inclusion and exclusion criteria, a total of 210 adult MHD patients were finally enrolled. Patients were categorized into two groups based on PEW diagnostic criteria, including 122 patients (58.1%) with PEW and 88 patients (41.9%) without PEW. We further analyzed the incidence of major adverse cardiovascular events (MACE) and all-cause mortality in one year, along with their risk factors.

resultsMACE incidence was significantly higher in the PEW group compared with the non-PEW group (

conclusionAdult MHD patients with PEW had an increased risk of MACE and all-cause mortality. Strategies aimed at optimizing total cholesterol, albumin, and prealbumin levels may improve cardiovascular outcomes in adult MHD patients with PEW.

Indexed as

Cardiovascular DiseasesProtein-Energy MalnutritionRenal DialysisAdultAgedChinaFemaleHumansIncidenceKidney Failure, ChronicMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsProportional Hazards ModelsRetrospective StudiesNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)hemodialysismajor adverse cardiovascular eventsmortalityProtein energy wastingrisk factors

Identifiers

PMID39694533
PMCPMC11656757

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.