Evidence map›Paper›PMID 39694887›Full record

GuidelineEuropean radiology2025

Soft tissue tumor imaging in adults: European Society of Musculoskeletal Radiology-Guidelines 2024: imaging immediately after neoadjuvant therapy in soft tissue sarcoma, soft tissue tumor surveillance, and the role of interventional radiology.

Iris-Melanie Noebauer-Huhmann, Joan C Vilanova, Olympia Papakonstantinou, Marc-André Weber, Radhesh K Lalam, Violeta Vasilevska Nikodinovska, Hatice T Sanal, Frédéric E Lecouvet, Ana Navas, José Martel-Villagrán and 41 more

Abstract readPractice Guideline
In one paragraph

Guideline in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Diagnosis and Management of Soft-Tissue Sarcomas: Current Insights.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

51 authors.

Iris-Melanie Noebauer-HuhmannDepartment of Biomedical Imaging and Image Guided Therapy, Division of Neuroradiology and Musculoskeletal Radiology, Medical University of Vienna, Vienna, Austria. iris.noebauer@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-6301-2784
Joan C VilanovaDepartment of Radiology, Clínica Girona, Institute of Diagnostic Imaging (IDI) Girona, University of Girona, Girona, Spain.
Olympia Papakonstantinou2nd Department of Radiology, Attikon Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Marc-André WeberInstitute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, University Medical Center Rostock, Rostock, Germany.
Radhesh K LalamDepartment of Radiology, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, UK.
Violeta Vasilevska NikodinovskaMedical Faculty, University "Ss. Cyril and Methodius", Skopje, North Macedonia.
Hatice T SanalRadiology Department, University of Health Sciences, Gülhane Training and Research Hospital, Ankara, Türkiye.
Frédéric E LecouvetDepartment of Radiology and Medical Imaging, Cliniques Universitaires Saint Luc, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II (IRA2), Université Catholique de Louvain (UCLouvain), Brussels, Belgium.
Ana NavasDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
José Martel-VillagránRadiology Department, Hospital Universitario Fundación Alcorcón, Madrid, Spain.
Jacky W J de RooyDepartment of Imaging, Radiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Jan FritzDepartment of Radiology, NYU Grossman School of Medicine, New York, USA.
Koenraad VerstraeteDepartment of Radiology, Ghent University Hospital, Ghent, Belgium.
Thomas GrieserDepartment for Diagnostic and Interventional Radiology, University Hospital Augsburg, Augsburg, Germany.
Pavol SzomolanyiHigh Field MR Center, Department of Biomedical Imaging and Image‑Guided Therapy, Medical University Vienna, Vienna, Austria.
Snehansh ChaudharyOxford University Hospitals NHS Foundation Trust, Oxford, UK.
Luca Maria SconfienzaIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Alberto S TagliaficoDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
P Diana AfonsoHospital Particular da Madeira, and Hospital da Luz Lisboa, Lisbon, Portugal.
Omar M AlbtoushDepartment of Radiology, University of Jordan, Ammam, Jordan.
Giacomo AringhieriAcademic Radiology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Remide ArkunEge University Medical School (Emeritus), Izmir, Türkiye.
Gunnar AströmDepartment of Immunology, Genetics and Pathology (including Oncology), Uppsala University, Uppsala, Sweden.
Alberto BazzocchiDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Rajesh BotchuDepartment of Musculoskeletal Radiology, Royal Orthopedic Hospital, Birmingham, UK.
Martin BreitenseherSigmund Freud Privatuniversität, Vienna, Austria.
Danoob DaliliAcademic Surgical Unit, South West London Elective Orthopaedic Centre (SWLEOC), London, UK.
Mark DaviesDepartment of Musculoskeletal Radiology, Royal Orthopedic Hospital, Birmingham, UK.
Milko C de JongeDepartment of Radiology, St. Antonius Hospital, Utrecht, The Netherlands.
Berna D MeteDepartment of Radiology School of Medicine, Izmir Demokrasi University, Izmir, Türkiye.
Jan L M A GielenDepartment of Radiology, Jessa Ziekenhuis, Campus Virga Jesse, Hasselt, Belgium.
Geoff HideDepartment of Radiology, Freeman Hospital, Newcastle Upon Tyne, UK.
Amanda IsaacSchool of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Slavcho IvanoskiSt. Erasmo Hospital for Orthopaedic Surgery and Traumatology Ohrid, Ohrid, North Macedonia.
Ramy M MansourOxford University Hospitals, Oxford, UK.
Catherine MccarthyOxford Musculoskeletal Radiology and Oxford University Hospitals, Oxford, UK.
Lorenzo Muntaner-GimbernatHospital Univeritario Son Espases Balearic Islands University, Palma, Spain.
Paul O'DonnellRoyal National Orthopaedic Hospital NHS Trust | RNOH · Department of Radiology, London, UK.
Şebnem ÖrgüçManisa Celal Bayar University, Manisa, Türkiye.
Winston J RennieClinical MSK Radiology, Loughborough University, Leicester Royal Infirmary, Leicester, UK.
Santiago ResanoHospital Universitario Ramón y Cajal, Madrid, Spain.
Philip RobinsonMusculoskeletal Radiology Department Chapel Allerton Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Simone A J Ter HorstPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Kirsten van LangeveldeDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Klaus WörtlerMusculoskeletal Radiology Section, Klinikum Rechts der Isar, Technical University of Munich ‑ TUM School of Medicine, Munich, Germany.
Marita KoelzDepartment of Pathology, Medical University of Vienna, Vienna, Austria.
Joannis PanotopoulosDepartment of Orthopaedics and Traumatology, Medical University of Vienna, Vienna, Austria.
Reinhard WindhagerDepartment of Orthopaedics and Traumatology, Medical University of Vienna, Vienna, Austria.
Barbara J FuegerDepartment of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria.
Maximilian SchmidDepartment of Radiation Oncology, Medical University of Vienna, Vienna, Austria.
Filip M VanhoenackerDepartment of Radiology AZ Sint Maarten Mechelen, University (Hospital) Antwerp, Antwerp, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAn update of the first European Society of Musculoskeletal Radiology (ESSR) consensus on soft tissue tumor imaging in 2015 became necessary due to technical advancements, further insights into specific entities, and the revised WHO classification (2020) and AJCC staging system (2017). The third part of the revised guidelines covers algorithms and techniques beyond initial imaging: (1) Imaging after neoadjuvant therapy in soft tissue sarcoma, (2) sarcoma surveillance, and (3) special aspects, including surveillance of non-malignant entities and the role of interventional radiology. MATERIALS AND

methodsA validated Delphi method based on peer-reviewed literature was used to derive consensus among a panel of 46 specialized musculoskeletal radiologists from 12 European countries. Statements that had undergone interdisciplinary revision were scored online by level of agreement (0 to 10) during two iterative rounds that could result in either 'group consensus,' 'group agreement,' or 'lack of agreement.'

resultsThe three sections contain 47 statements with comments. Group consensus was reached in 91.5%, group agreement in 6.4%, lack of agreement in 2.1%. In sarcoma, imaging immediately after neoadjuvant therapy is pivotal for determining the therapy effects and for resection-planning; surveillance should include imaging at fixed grade- and type-dependent intervals. In general, MRI is the method of choice for loco-regional surveillance of soft tissue sarcomas, and chest CT to assess metastatic disease. Interventional radiology has a role, especially in oligometastatic disease, palliative tumor control and local recurrences.

conclusionStrategies for standardized soft tissue tumor imaging regarding therapy control, surveillance, and useful interventional procedures are provided. KEY POINTS: Question An ESSR consensus update on soft tissue tumor imaging regarding surveillance became necessary due to technical advancements, further entity-specific insights, and revised WHO- and AJCC-classifications. Findings Imaging immediately after neoadjuvant therapy in soft tissue sarcoma is pivotal. Post-therapeutic surveillance should include imaging at regular intervals, stratified for tumor grade and type. Clinical relevance The updated ESSR soft tissue tumor imaging guidelines aim to provide best practice expert consensus for standardized imaging, to support radiologists in their decision-making, and to improve examination comparability, both in individual patients and in future studies on individualized strategies.

Indexed as

Radiology, InterventionalSarcomaSoft Tissue NeoplasmsAdultConsensusDelphi TechniqueEuropeHumansNeoadjuvant TherapySocieties, MedicalConsensusDiagnostic imagingPractice guidelineSarcoma (Soft tissue)Soft tissue neoplasms

Identifiers

PMID39694887
PMCPMC12081562

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.