ArticleNature2025
Nucleosome fibre topology guides transcription factor binding to enhancers.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
–field-weighted citation impact
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Who cites it
22 citing papers in PubMed.
- Autolysosomal enhancer GHF201 attenuates pathophysiology in a mucopolysaccharidosis type I mouse model.Life science alliance · 2026Article
- Massively parallel characterization and predictive modelling of neuronal regulatory variation.bioRxiv : the preprint server for biology · 2026Article
- CAD-C: An engineered nuclease enables repair-freebioRxiv : the preprint server for biology · 2026Article
- Multi-Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean-Type and Chinese Indigenous Pigs.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Differential protein network and biological functions atlas from multi-tissue proteomics in patients with depression.Molecular psychiatry · 2026Article
- Article
- DNA Mechanical Strain Steers Transcription Factor Recognition.Research square · 2026Article
- Article
- Elastic enhancer network tunes equilibrium thermodynamics of liquid liquid phase separation in super enhancers.iScience · 2026Article
- From Natural Discovery to AI-Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Nucleosome spacing across cell types, diseases, and ages.Nucleic acids research · 2026Review
- baal-nf identifies motif-disrupting variants that decrease transcription factor binding affinity.Genome biology · 2026Article
- Feed-forward loops by NR5A2 ensure robust gene activation during pre-implantation development.Development (Cambridge, England) · 2026Article
- Uncovering the Mechanistic Landscape of Regulatory DNA with Deep Learning.bioRxiv : the preprint server for biology · 2025Article
- Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4.Nature communications · 2025Article
- Systematic DNA nicking reveals the structural logic of protein recognition.bioRxiv : the preprint server for biology · 2025Article
- Aere perennius: how chromatin fidelity is maintained and lost in disease.NAR molecular medicine · 2025Review
- Mechanosensitive nuclear checkpoint: nuclear envelope as a sensor of chromosomal instability and driver of cell fate.Mechanobiology in medicine · 2025Article
- Compromised two-start zigzag chromatin folding in immature mouse retina cells driven by irregularly spaced nucleosomes with short DNA linkers.Nucleic acids research · 2025Article
- Towards Precision Aging Biology: Single-Cell Multi-Omics and Advanced AI-Driven Strategies.Aging and disease · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Michael R O'DwyerInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-1371-1421
Meir Azagury *Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Katharine Furlong *Institute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.ORCID 0009-0001-3268-0763
Amani AlsheikhInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.
Elisa Hall-PonseleInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.
Hugo PintoDepartment of Cell Biology, Albert Einstein College of Medicine, New York, NY, USA.
Dmitry V FyodorovDepartment of Cell Biology, Albert Einstein College of Medicine, New York, NY, USA.
Mohammad JaberDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Eleni PapachristoforouInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-1553-1405
Hana BenchetritDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
James AshmoreInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.
Kirill MakedonskiDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Moran RahamimDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Marta HanzevackiInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.
Hazar YassenDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Samuel SkodaInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.ORCID 0009-0006-2742-0146
Adi LevyDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Steven M PollardInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-6428-0492
Arthur I SkoultchiDepartment of Cell Biology, Albert Einstein College of Medicine, New York, NY, USA.
Yosef BuganimDepartment of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel. yossib@ekmd.huji.ac.il.ORCID 0000-0002-7970-5163
Abdenour SoufiInstitute of Regeneration and Repair, Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, UK. Abdenour.Soufi@ed.ac.uk.ORCID 0000-0002-3666-3266
Funding
Functions of Mammalian H1 Linker Histones in Gene Regulation and Chromatin ActivityR01GM147165 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI SKOULTCHI, ARTHUR I · 2022 to 2025
$2.1MSperm chromatin structure and remodeling during spermiogenesis and fertilizationR01HD114814 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DMITRY V FYODOROV · 2024 to 2026
$1.7MNICHD NIH HHS R01 HD114814NIGMS NIH HHS R01 GM147165
Abstract
Cellular identity requires the concerted action of multiple transcription factors (TFs) bound together to enhancers of cell-type-specific genes. Despite TFs recognizing specific DNA motifs within accessible chromatin, this information is insufficient to explain how TFs select enhancers
Indexed as
Enhancer Elements, GeneticNucleosomesTranscription FactorsAnimalsBinding SitesCell LineageChromatinHumansMiceNucleotide MotifsProtein BindingChromatinNucleosomesTranscription Factors
Identifiers
What Socratic holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.