Evidence mapPaperPMID 39695586Full record

Observational studyBMC health services research2024

Pharmacist-led interventions for vascular surgery patients: a prospective study on reducing drug-related problems.

Slavka Porubcova, Kristina Szmicsekova, Kristina Lajtmanova, Veronika Slezakova, Michal Jakubik, Eva Drobna, Jan Tomka, Zuzana Kobliskova, Lucia Masarykova, Lubica Lehocka and 1 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMC health services research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04930302 (Optimizing the Pharmacotherapy of Vascular Surgery Patients at Hospital Admission, at Discharge and at Post-discharge Check-up), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04930302 completednot on this map

Optimizing the Pharmacotherapy of Vascular Surgery Patients at Hospital Admission, at Discharge and at Post-discharge Check-up: Quasi-experimental Clinical Uncontrolled Trial (PHAROS)

TypeobservationalSponsorNational Institute of Cardiovascular Diseases, SlovakiaRan2021 to 2023Enrolled105ConditionsMedication Errors and Other Product Use Errors and Issues
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Slavka PorubcovaHospital Pharmacy, The National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
Kristina SzmicsekovaHospital Pharmacy, The National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
Kristina LajtmanovaHospital Pharmacy, The National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
Veronika SlezakovaHospital Pharmacy, The National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
Michal JakubikMIA Solutions, Bratislava, Slovakia.
Eva DrobnaDepartment of Informatics, Armed Forces Academy of General Milan Rastislav Stefanik, Liptovsky Mikulas, Slovakia.
Jan TomkaDepartment of Vascular Surgery, The National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
Zuzana KobliskovaDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Lucia MasarykovaDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Lubica LehockaDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia.
Tomas TesarDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovakia. tesar@fpharm.uniba.sk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular surgery patients are at a high risk of polypharmacy and drug-related problems. Only a limited number of studies have explored the impact of hospital pharmacists being members of a multidisciplinary team in the care of vascular surgery patients. The clinical study (Trial Registration Number NCT04930302, 16

methodsThe study, conducted at a specialised hospital in Slovakia during a 1-year period, included adult patients with carotid artery disease or lower extremity artery disease, taking ≥3 medications. Medication reconciliation and medication reviews were performed by hospital pharmacists at both admission and discharge. Pharmacist-proposed interventions were documented and communicated to the physician, patients were educated about their medications upon discharge.

resultsAmong our study participants (n = 105), the average number of drug-related problems at admission was 2.3 ± 2.1, significantly decreasing to 1.6 ± 1.8 at discharge (p < 0.001). The predominant drug classes associated with drug-related problems were those related to the cardiovascular system (41.9%). At admission, the most frequent drug-related problem was untreated indication (40.3%), mostly caused by the failure to prescribe statin in patients with lower extremity artery disease. The highest acceptance rate of pharmacist-led interventions was at hospital admission (66.1%). More than 50% of patients were classified as those with good understanding of their pharmacotherapy.

conclusionsThis study demonstrates that pharmacist-led interventions significantly reduce drug-related problems in vascular surgery patients during hospitalisation, contributing to patient safety and clinical outcomes.

trial registrationClinicalTrials.gov Trial Registration Number: NCT04930302, 16

Indexed as

Medication ReconciliationPharmacistsPharmacy Service, HospitalVascular Surgical ProceduresAgedAged, 80 and overDrug-Related Side Effects and Adverse ReactionsFemaleHumansMaleMiddle AgedPeripheral Arterial DiseasePolypharmacyProspective StudiesSlovakiaDrug-related problemMedication reconciliationMedication reviewPatient educationPharmaceutical care

Identifiers

PMID39695586
PMCPMC11653549

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.