Evidence map›Paper›PMID 39696510›Full record

SynthesisEuropean journal of medical research2024

Red blood cell distribution width at admission and the short-term mortality of patients with severe burn injury: a meta-analysis.

Qing Cao, Xiafei He, Xiuhuang Chen, Xing Han, Lutao Yang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qing CaoDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, No. 48 Taling Nanlu, Jiujiang, 332000, Jiangxi, China.
Xiafei HeDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, No. 48 Taling Nanlu, Jiujiang, 332000, Jiangxi, China.
Xiuhuang ChenDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, No. 48 Taling Nanlu, Jiujiang, 332000, Jiangxi, China.
Xing HanDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, No. 48 Taling Nanlu, Jiujiang, 332000, Jiangxi, China.
Lutao YangDepartment of Burn Plastic and Wound Repair, Jiujiang City Key Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, No. 48 Taling Nanlu, Jiujiang, 332000, Jiangxi, China. ltyangjjh@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRed blood cell distribution width (RDW) is a marker of inflammation and oxidative stress, and its elevation has been associated with poor outcomes in critically ill patients. This meta-analysis aimed to evaluate the association between RDW at admission and short-term mortality in patients with severe burn injury.

methodsWe systematically searched PubMed, Embase, and Web of Science up to August 2024, following PRISMA 2020 and Cochrane guidelines. Cohort studies of adult severe burn patients who reported RDW at admission and short-term mortality were included. Meta-analyses were performed using random-effects models, with mean difference (MD) and relative risk (RR) calculated for RDW and mortality outcomes, respectively. Subgroup and sensitivity analyses were conducted to assess heterogeneity.

resultsNine cohort studies involving 5268 patients were included. Overall, RDW at admission was higher in nonsurvivors compared to survivors [MD: 0.95%, 95% confidence interval (CI): 0.52-1.38, p < 0.001, I

conclusionsRDW at admission is a significant predictor of short-term mortality in patients with severe burn injury. This finding highlights the potential role of RDW as a simple and effective marker for risk stratification in these patients.

Indexed as

BurnsErythrocyte IndicesBiomarkersHumansPrognosisBiomarkersMeta-analysisMortalityRed blood cell distribution widthRisk factorSevere burn

Identifiers

PMID39696510
PMCPMC11658159

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.