Evidence map›Paper›PMID 39696714›Full record

ArticleBiological research2024

A snapshot of cancer in Chile II: an update on research, strategies and analytical frameworks for equity, innovation and national development.

Cristóbal Vacarezza, Julieta Araneda, Pamela Gonzalez, Oscar Arteaga, Katherine Marcelain, Enrique A Castellon, Ana Periera, Maroun Khoury, Bettina Müller, Juan Alberto Lecaros and 9 more

Abstract read
In one paragraph

Article in Biological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Cristóbal Vacarezza *Medical Public Health Residency Program, School of Public Health Dr. Salvador Allende, Faculty of Medicine, Universidad de Chile, Independencia 939, Santiago, Chile.
Julieta Araneda *Public Health Program, School of Public Health Dr. Salvador Allende, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Pamela GonzalezFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Alameda 340, 8331150, Santiago, Chile.
Oscar ArteagaSchool of Public Health Dr. Salvador Allende, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Katherine MarcelainCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Enrique A CastellonCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Ana PerieraInstitute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.
Maroun KhouryLaboratory of Nano-Regenerative Medicine, Faculty of Medicine, Universidad de Los Andes, Santiago, Chile.
Bettina MüllerCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Juan Alberto LecarosBioethics and Law Observatory, Institute of Sciences and Innovation in Medicine, Universidad del Desarrollo, Santiago, Chile.
Sofia P SalasCenter for Bioethics, Faculty of Medicine, Clinica Alemana, Universidad del Desarrollo Santiago, Santiago, Chile.
Arnoldo RiquelmeCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Alejandro H CorvalanDepartment of Hematology and Oncology, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Jorge Jiménez de la JaraCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Catterina FerreccioCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Carolina GoicCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Bruno NerviCenter for Cancer Prevention and Control (FONDAP-CECAN), Pontificia Universidad Católica de Chile and Universidad de Chile, Santiago, Chile.
Juan Carlos RoaMillennium Institute on Immunology and Immunotherapy, 8331150, Santiago, Chile.
Gareth I OwenFaculty of Biological Sciences, Pontificia Universidad Católica de Chile, Alameda 340, 8331150, Santiago, Chile. gowen@bio.puc.cl.ORCID http://orcid.org/0000-0003-3807-6054

Funding

ANID-Anillo ACT210079ANID-Basal FB210024ANID FONDAP 152220002ANID-FONDAP 15130011ANID-FONDAP 1523A0008ANID-FONDECYT 1220586HORIZON EUROPE Framework Programme 825741Instituto Milenio en Inmunología e Inmunoterapia ICN2021_045Instituto Milenio en Inmunología e Inmunoterapia PROGRAMA ICM-ANID
6 · The paper itself

Abstract

introductionChile has achieved developed nation status and boasts a life expectancy of 81 + years; however, the healthcare and research systems are unprepared for the social and economic burden of cancer. One decade ago, the authors put forward a comprehensive analysis of cancer infrastructure, together with a series of suggestions on research orientated political policy.

objectivesProvide an update and comment on policy, infrastructure, gender equality, stakeholder participation and new challenges in national oncology. Assess the funding and distribution of cancer investigation. Present actions for the development of oncology research, innovation and patient care.

methodsTriangulating objective system metrics of economic, epidemiological, private and public sector resources together with policy analysis, we assessed cancer burden, infrastructure, and investigation. We analyzed governmental and private-sector cancer databases, complemented by interviews with cancer stakeholders.

resultsGovernmental policy and patient advocacy have led to the recognition of cancer burden, a cancer law, and a national cancer plan. Cancer has become the leading cause of death in Chile (59,876 cases and 31,440 cancer deaths in 2022), yet only 0.36% gross domestic product (GDP) is directed to research and development. Inequalities in treatment regimens persist. Prevention policy has lowered tobacco consumption, sugar intake via soft drinks and offered a high coverage of HPV vaccines. A high-quality cancer research community is expanding, and internationally sponsored clinical oncology trials are increasing.

conclusionsThe cancer law has facilitated advancement in policy. Prevention policies have impacted tobacco and sugar intake, while gender equality and care inequality have entered the public forum. Cancer research is stagnated by the lack of investment. Implementation of a cancer registry and biobanking, reinforcement of prevention strategies, development of human resources, promotion of clinical trial infrastructure and investment in new technologies must be placed as a priority to permit advancements in innovation and equitable cancer care.

Indexed as

NeoplasmsBiomedical ResearchChileFemaleHealth PolicyHumansChileClinical trialsIncidencePolicyResearchSouth-America

Identifiers

PMID39696714
PMCPMC11657627

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.