Evidence map›Paper›PMID 39697587›Full record

ArticleOncology reviews2024

Investigation of the prevalence of latent tuberculosis in cancer patients compared to non-cancer patients: a case-control study.

Masoud Mortezazadeh, Mehdi Karimi, Mohsen Esfandbod, Abbas Mofidi, Nima Hemmati, Mehdi Kashani, Niyousha Shirsalimi, Seyyed Taher Seyyed Mahmoudi, Ehsan Kamali Yazdi

Abstract read
In one paragraph

Article in Oncology reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Multiple Pyogenic Arthritis Caused byCase reports in infectious diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Masoud MortezazadehDepartment of Hematology-Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Mehdi KarimiFaculty of Medicine, Bogomolets National Medical University (NMU), Kyiv, Ukraine.
Mohsen EsfandbodDepartment of Hematology-Oncology, Sina Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Abbas MofidiMinimally Invasive Surgery Research Center (MISRC), Iran University of Medical Sciences (IUMS), Tehran, Iran.
Nima HemmatiMinimally Invasive Surgery Research Center (MISRC), Iran University of Medical Sciences (IUMS), Tehran, Iran.
Mehdi KashaniFaculty of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Niyousha ShirsalimiFaculty of Medicine, Hamadan University of Medical Science (UMSHA), Hamadan, Iran.
Seyyed Taher Seyyed MahmoudiFaculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Ehsan Kamali YazdiFaculty of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Latent tuberculosis (TB) can reactivate in immunocompromised individuals, such as cancer patients undergoing chemotherapy, leading to severe complications. Understanding the prevalence of latent TB in this high-risk group is crucial, especially in regions with moderate to high TB burdens. Aim: This study aims to determine the prevalence of latent tuberculosis in cancer patients before chemotherapy and immunotherapy to guide preventive interventions and reduce the risk of TB reactivation. Methods: This case-control study was conducted at Sina Hospital in Tehran, Iran, from 2012 to 2022. A total of 392, including 107 newly diagnosed cancer (case) and 285 non-cancer (control) patients, were enrolled in this study. All patients had received the Results: The results showed no significant difference in the size of TST between cancer and non-cancer patients (cases: median = 2 mm, IQR: 1-12; controls: median = 2 mm, IQR: 1-5; Conclusion: In conclusion, this study emphasizes the need for vigilant latent TB screening in cancer patients, given the association between larger TST sizes and increased mortality risk. While no direct link between cancer type and latent TB was found, proactive TB management remains crucial, particularly for those undergoing immunosuppressive therapy.

Indexed as

cancerinfectious diseaseMycobacteriumoncologytuberculin skin testtuberculosis

Identifiers

PMID39697587
PMCPMC11652964

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.