ArticleCureus2024
A Rare Case of an Aggressive Mixed Germ Cell Tumor Following Testicular Torsion.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Article
- Testicular Embryonal Carcinoma With Retroperitoneal Metastasis and Normal AFP and HCG: A Case Report.Case reports in oncological medicine · 2026Article
- Primary Choriocarcinoma in Two Male Patients: A Case Report.Clinical case reports · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Testicular cancer is one of the leading malignancies affecting young men, with germ cell tumors (GCTs) being the most prevalent type. These tumors are classified into two main subtypes: seminomas and non-seminomatous germ cell tumors (NSGCTs), with the latter known for their higher likelihood of metastasis. Early detection through imaging and tumor markers like alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (HCG) is crucial for favorable outcomes. We present a case of a 40-year-old male patient with a recent history of a surgically repaired right testicular torsion presenting with progressive right testicular swelling and pain. Scrotal ultrasound revealed a markedly enlarged and heterogeneous right testicle measuring 5.4 cm, with mixed echogenicity and cystic features, highly suspicious for malignancy. Tumor markers were significantly elevated, with AFP at 19,420 ng/mL and HCG at 4,749 mIU/mL, indicating a high-risk testicular tumor. The patient underwent a right radical orchiectomy, which was complicated by tumor rupture during surgery. Pathology confirmed a testicular mixed GCT composed of embryonal carcinoma, yolk sac tumor, and teratoma with vascular/lymphatic invasion. This case highlights the importance of rapid intervention in managing NSGCTs, potential role of tumors in testicular torsions, and the unusual presentation of a rapidly growing NSGCT.
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