ArticleQuantitative imaging in medicine and surgery2024
Coronary computed tomography angiography for assessing the coronary artery and predicting adverse cardiovascular events in patients with thoracic malignancies.
Article in Quantitative imaging in medicine and surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Correlation Between Fat Attenuation Index and Major Adverse Cardiovascular Events: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2026Pooled it
- Pericoronary fat attenuation index and major adverse cardiovascular events: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2026Article
- Explainable ML for ACS culprit plaques: a multidimensional CCTA model highlighting hemodynamic increment.The international journal of cardiovascular imaging · 2026Article
- Plaque characteristics and parameters derived from coronary computed tomography angiography for predicting major adverse cardiovascular events in patients with and without diabetes.Quantitative imaging in medicine and surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: It is unclear whether the parameters derived from coronary computed tomography angiography (CCTA) can identify the impairments of coronary arteries and if they are associated with major adverse cardiovascular events (MACEs) in patients with thoracic malignancies receiving chemotherapy or chemoradiotherapy. This study aimed to investigate the longitudinal changes in coronary arteries using CCTA and to determine their association with MACEs in patients with thoracic malignancies receiving chemotherapy or chemoradiotherapy. Methods: This cross-sectional study included consecutive patients with thoracic malignancies who received chemotherapy or chemoradiotherapy and who underwent CCTA between June 2013 and May 2019 at Chongqing University Cancer Hospital. The pericoronary fat attenuation index (FAI) of three main coronary arteries before and after chemotherapy or chemoradiotherapy were assessed. The association between CCTA parameters and MACEs was evaluated via the Cox proportional hazards model. Kaplan-Meier survival curves were drawn to compare the MACE-free survival rates. Results: A total of 1,543 patients were enrolled, 232 of whom developed MACEs. Among the patients, 41.3% were male, and the median age was 67.00 years (interquartile range 56.00-72.00 years). The FAI values were significantly increased after chemotherapy or chemoradiotherapy (all P values <0.05). After treatment, the FAI values were higher in the chemoradiotherapy group than in the chemotherapy group. MACEs were associated with the FAI values before chemotherapy in the left anterior descending artery (LAD), left circumflex artery (LCX), and right coronary artery (RCA) [LAD: hazard ratio (HR) =3.745, 95% confidence interval (CI): 1.193-11.756, P=0.023; LCX: HR =3.460, 95% CI: 1.092-10.832, P=0.031; RCA: HR =4.175, 95% CI: 1.375-12.673, P=0.011] and chemoradiotherapy (LAD: HR =2.856, 95% CI: 1.210-6.742, P=0.016; LCX: HR =2.385, 95% CI: 1.037-5.487; P=0.040; RCA: HR =2.029, 95% CI: 1.074-3.834, P=0.029). Conclusions: The FAI derived from CCTA, as an imaging biomarker of coronary arterial inflammation, was able to characterize coronary arterial impairment, and the FAI at baseline was associated with MACEs in patients with thoracic malignancies receiving chemotherapy or chemoradiotherapy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.