Evidence map›Paper›PMID 39699231›Full record

ArticlemSphere2025

The

Harley O'Connor Mount, Malene L Urbanus, Francesco Zangari, Anne-Claude Gingras, Alexander W Ensminger

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Harley O'Connor Mount *Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-1401-9178
Malene L Urbanus *Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0009-0008-0850-3805
Francesco ZangariDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0009-0000-7531-642X
Anne-Claude GingrasDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-6090-4437
Alexander W EnsmingerDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-0824-3704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eukaryotic CCR4-NOT deadenylase complex is a highly conserved regulator of mRNA metabolism that influences the expression of the complete transcriptome, representing a prime target for a generalist bacterial pathogen. We show that a translocated bacterial effector protein, PieF (Lpg1972) of IMPORTANCE: The intracellular bacterial pathogen

Indexed as

Bacterial ProteinsHost-Pathogen InteractionsLegionella pneumophilaRibonucleasesRNA StabilityExoribonucleasesHumansProtein BindingRepressor ProteinsRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsBacterial ProteinsCNOT7 protein, humanExoribonucleasesPOP2 protein, S cerevisiaeRepressor ProteinsRibonucleasesRNA, MessengerSaccharomyces cerevisiae ProteinsCaf1CCR4-NOTCNOT7/8CNOT7 inhibitiondeadenylationDEDDeffectorshost-pathogen interactionLegionella pneumophilamRNA stabilityPieFPop2

Identifiers

PMID39699231
PMCPMC11774319

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.