Evidence map›Paper›PMID 39699511›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2024

Seroprevalence of Strongyloides stercoralis, human T-lymphotropic virus, and Chagas disease in the Peruvian Amazon: a cross-sectional study.

Martin Casapía-Morales, Wilma-Selva Casanova-Rojas, Jhosephi Vázquez-Ascate, Cristiam-Armando Carey-Angeles, Carlos Alvarez-Antonio, Freddy-Franco Alava-Arévalo, Silvia Otero-Rodríguez, José-Manuel Ramos-Rincón

Abstract read
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin Casapía-MoralesUniversidad Nacional de la Amazonia Peruana, Facultad de Medicina Humana, Iquitos, Peru.ORCID http://orcid.org/0000-0002-5972-0948
Wilma-Selva Casanova-RojasUniversidad Nacional de la Amazonia Peruana, Facultad de Medicina Humana, Iquitos, Peru.
Jhosephi Vázquez-AscateUniversidad Nacional de la Amazonia Peruana, Facultad de Medicina Humana, Iquitos, Peru.
Cristiam-Armando Carey-AngelesUniversidad Nacional de la Amazonia Peruana, Facultad de Medicina Humana, Iquitos, Peru.
Carlos Alvarez-AntonioMinisterio de Salud del Peru, Iquitos, Peru.
Freddy-Franco Alava-ArévaloMinisterio de Salud del Peru, Iquitos, Peru.
Silvia Otero-RodríguezHospital Universitario General Dr. Balmis, Departamento de Medicina Interna, Alicante, Spain.ORCID http://orcid.org/0000-0002-7801-5072
José-Manuel Ramos-RincónHospital Universitario General Dr. Balmis, Departamento de Medicina Interna, Alicante, Spain.ORCID http://orcid.org/0000-0002-6501-9867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strongyloides stercoralis infections, human T-lymphotropic virus (HTLV) infections, and Chagas diseases occur throughout many regions of Central and South America, including Peru. This study aimed to evaluate the seroprevalence of S. stercoralis, HTLV, and Chagas disease in Iquitos (Peruvian Amazon) and the associated epidemiological conditions for S. stercoralis seroprevalence in Iquitos. A population-based cross-sectional study was conducted from May 1 to June 15, 2020, to assess the seroprevalence of S. stercoralis [lysate antigen ELISA (enzyme linked immunosorbent assay)], HTLV (recombinant antigen ELISA), and Chagas disease (crude and recombinant antigen ELISAs). Of the 396 included individuals, 257 were seropositive for S. stercoralis (a 64.9% prevalence, 95% confidence interval [CI] 60.0% to 69.4%). In the multivariable analysis, seropositivity for S. stercoralis was higher in women (odds ratio [OR] 1.60, 95% CI 1.03 to 2.66) and residents of Punchana (OR 3.47, 95% CI 1.51 to 7.93), whereas residence in Iquitos was associated with lower positivity (OR 0.52, 95% CI 0.32 to 0.85). In total, four individuals were positive for HTLV (1.0% seroprevalence, 95% CI 0.3% to 2.7%), and none were positive for Chagas disease (0.0% seroprevalence, 95% CI 0.0% to 1.2%). The seroprevalence of S. stercoralis in Iquitos is high, particularly among women and residents of Punchana. The presence of HTLV infection indicates that the virus is circulating in Iquitos. This study found no cases of Chagas disease.

Indexed as

Chagas DiseaseEnzyme-Linked Immunosorbent AssayStrongyloides stercoralisStrongyloidiasisAdolescentAdultAgedAnimalsAntibodies, HelminthChildCross-Sectional StudiesFemaleHTLV-I InfectionsHumansMaleMiddle AgedAntibodies, Helminth

Identifiers

PMID39699511
PMCPMC11654120

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.