Evidence map›Paper›PMID 39703231›Full record

ArticlePNAS nexus2024

In silico prediction of pathogen's pandemic potential using the viral trait assessment for pandemics (ViTAP) model.

Charles H Jones, Marie Beitelshees, B Adam Williams, Andrew B Hill, Verna L Welch, Jane M True

Abstract read
In one paragraph

Article in PNAS nexus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charles H JonesPfizer, 66 Hudson Boulevard, New York, NY 10018, USA.ORCID https://orcid.org/0009-0004-0368-6463
Marie BeitelsheesBulmore Consulting, Lockport, NY 14094, USA.ORCID https://orcid.org/0000-0003-2238-4431
B Adam WilliamsPfizer, 66 Hudson Boulevard, New York, NY 10018, USA.ORCID https://orcid.org/0009-0001-1558-9562
Andrew B HillBulmore Consulting, Lockport, NY 14094, USA.
Verna L WelchPfizer, 66 Hudson Boulevard, New York, NY 10018, USA.
Jane M TruePfizer, 66 Hudson Boulevard, New York, NY 10018, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our world is ever evolving and interconnected, creating constant opportunities for disease outbreaks and pandemics to occur, making pandemic preparedness and pathogen management crucial for global health security. Early pathogen identification and intervention play a key role in mitigating the impacts of disease outbreaks. In this perspective, we present the Viral Trait Assessment for Pandemics (ViTAP) model to aid in the early identification of high-risk viruses that have pandemic potential, which incorporates lessons from past pandemics, including which key viral characteristics are important such as genetic makeup, transmission modes, mutation rates, and symptom severity. This model serves as the foundation for the development of powerful, quantitative tools for the early prediction of pandemic pathogens. The use of such a tool, in conjunction with other pandemic preparedness measures, can allow for early intervention and containment of the virus. This proactive approach could enable timely interventions, guiding public health responses, and resource allocation to prevent widespread outbreaks and mitigate the impact of emerging pathogens.

Identifiers

PMID39703231
PMCPMC11658415

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.