Evidence map›Paper›PMID 39703514›Full record

ReviewFrontiers in immunology2024

The antioxidant barrier, oxidative/nitrosative stress, and protein glycation in allergy: from basic research to clinical practice.

Grzegorz Biedrzycki, Blanka Wolszczak-Biedrzycka, Justyna Dorf, Mateusz Maciejczyk

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Oxidative and Nitrosative Stress in Atopic Dermatitis and Depression: Similarities in Biomarkers and Pathophysiological Mechanisms.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  4. Article
  5. The Role of Ethyl Acetate Fraction fromMolecules (Basel, Switzerland) · 2026
    Article
  6. Ameliorating Effects ofAntioxidants (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Grzegorz BiedrzyckiHospital Pharmacy, Provincial Psychiatric Hospital, Olsztyn, Poland.
Blanka Wolszczak-BiedrzyckaDepartment of Psychology and Sociology of Health and Public Health, University of Warmia and Mazury, Olsztyn, Poland.
Justyna DorfDepartment of Clinical Laboratory Diagnostics, Medical University of Bialystok, Bialystok, Poland.
Mateusz MaciejczykDepartment of Hygiene, Epidemiology and Ergonomics, Medical University of Bialystok, Bialystok, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies indicate that oxidative/nitrosative stress is involved in the pathogenesis of asthma, allergic rhinitis, atopic dermatitis, and urticaria. The article aimed to review the latest literature on disruptions in redox homeostasis and protein glycation in allergy patients. It has been shown that enzymatic and non-enzymatic antioxidant systems are impaired in allergic conditions, which increases cell susceptibility to oxidative damage. Reactive oxygen/nitrogen species exacerbate the severity of asthma symptoms by activating inflammatory mediators that cause airway smooth muscle contraction, promote mucus hypersecretion, increase the permeability of lung capillaries, and damage cell membranes. Redox biomarkers could have considerable diagnostic potential in allergy patients. There is no compelling evidence to indicate that antioxidants reduce allergy symptoms' severity or slow disease progression.

Indexed as

AntioxidantsHypersensitivityNitrosative StressOxidative StressAnimalsBiomarkersGlycation End Products, AdvancedGlycosylationHumansOxidation-ReductionReactive Oxygen SpeciesAntioxidantsBiomarkersGlycation End Products, AdvancedReactive Oxygen Speciesallergyantioxidantsnitrosative stressoxidative stressprotein glycation

Identifiers

PMID39703514
PMCPMC11655330

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.