← Diet, exercise & lifestyle × cardiovascular events

TrialJCI insight2024

Fasting substrates predict chronic kidney disease progression in CREDENCE trial patients with type 2 diabetes.

Ele Ferrannini et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 2024

Randomised comparison

Probably reduced cardiovascular events

−27%−46% to −2%

Bigger than 6 in 10 for cardiovascular events

As reported

HR 0.73, 95% CI 0.54–0.98

Randomised comparison

Probably reduced cardiovascular events

−33%−52% to −5%

Bigger than 7 in 10 for cardiovascular events

As reported

HR 0.67, 95% CI 0.48–0.95

Randomised comparison

Probably reduced cardiovascular events

−30%−50% to −1%

Bigger than 7 in 10 for cardiovascular events

As reported

HR 0.70, 95% CI 0.50–0.99

Randomised comparison

Probably reduced cardiovascular events

−37%−58% to −6%

Bigger than 8 in 10 for cardiovascular events

As reported

HR 0.63, 95% CI 0.42–0.94

Four numbers in the abstract

the abstract, start to end

… a lower risk of CKD progression (HR = 0.73 [95% CI: 0.54-0.98] and HR = 0.67 [95% CI: 0.48-0.95], respectively) and hHF/CVD HR = 0.70 [95% CI: 0.50-0.99] and HR = 0.63 [95% CI: 0.42-0.94]).

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
HR 0.730.54–0.98
Cardiovascular events
HR 0.670.48–0.95
Cardiovascular events
HR 0.700.50–0.99
Cardiovascular events
HR 0.630.42–0.94
Diet, exercise & lifestyleCardiovascular events

Diet, exercise & lifestyle × cardiovascular eventshelps?one trial

unlikelylikely
0.500.25 without it
← favours treatmentfavours comparator →
this papermore certainless certain
1 / 5

Not cited yet

Full record →Abstract, authors, funding and every citing paper · PMID 39704168