ArticleClinical neuroradiology2025
Microstructural Characteristics of Cervical Spinal Cord Using High Angular Resolution Diffusion Imaging (HARDI) and Tractography in Healthy Subjects.
Article in Clinical neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Stitching brain and spinal cord DTI using cross-correlation registration: toward an atlas of spinal tracts.European radiology experimental · 2025Article
- Mapping global research landscape and trends in magnetic resonance imaging applications for primary trigeminal neuralgia: a bibliometric analysis.Neurosurgical review · 2025Review
- Magnetic resonance tractography of the cervical spine: A rapid diffusion tensor imaging protocol to serve as a clinical evaluation tool.World journal of radiology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to characterize spinal cord microstructure in healthy subjects using high angular resolution diffusion imaging (HARDI) and tractography.
methodsForty-nine healthy subjects (18-50 years, divided into 2 age groups) were included in a prospective study. HARDI of the cervical spinal cord were acquired using a 3T MRI scanner with: 64 directions, b‑value: 1000s/mm
resultsThe microstructural organization of the spinal cord differed between upper and lower cervical spine levels: FA, and AD significantly decreased (p < 0.001); and RD significantly increased (p < 0.05) in lower levels, demonstrating changes in axonal density and myelinated fibers according to a cranio-caudal axis. FA, MD, AD, and RD values were significantly higher in spinal cord white matter (p < 0.0001), compared to grey matter. Age was not associated with a significant change in FA, while there is for MD, AD and RD (p < 0.05). Spinal cord tractography may provide information on the architectural organization of fibers and spinal tracts.
conclusionThis study proposes a database in cervical spinal cord HARDI, allowing to study the microstructural organization of the spinal cord in healthy subjects, and providing a foundation for comparison with patients presenting spinal cord pathologies.
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Identifiers
39704830What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.