Evidence map›Paper›PMID 39704911›Full record

ReviewMedical oncology (Northwood, London, England)2024

Nanotheranostics for gynecological cancers: a path forward for Africa.

Mutia Kehwalla Aza, Anavami Suberu, Mahmood Balogun, Goodness Adegbola, Mohamed Alie Sankoh, Thomas Oyediran, Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Chinonyelum Emmanuel Agbo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mutia Kehwalla AzaJohns Hopkins University, Bloomberg School of Public Health, Baltimore, USA.
Anavami SuberuUniversity of Ilorin, Ilorin, Nigeria.
Mahmood BalogunUniversity of Ilorin, Ilorin, Nigeria.
Goodness AdegbolaUniversity of Mississippi Medical Center, Jackson, MS, USA.
Mohamed Alie SankohNanjing Medical University, Nanjing, China.
Thomas OyediranLadoke Akintola University of Technology, Ogbomoso, Nigeria.
Nicholas AderintoLadoke Akintola University of Technology, Ogbomoso, Nigeria.
Gbolahan OlatunjiJohns Hopkins University, Bloomberg School of Public Health, Baltimore, USA.
Emmanuel KokoriUniversity of Ilorin, Ilorin, Nigeria.
Chinonyelum Emmanuel AgboDepartment of Clinical Pharmacy and Pharmacy Management, University of Nigeria, Nsukka, Nigeria. chinonyelumagbo1010@gmail.com.ORCID http://orcid.org/0009-0001-3744-3038

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle-based therapies represent a transformative approach to managing gynecological cancers, offering targeted treatment strategies that minimize harm to healthy tissues while maximizing therapeutic efficacy. Despite their potential, implementing these advanced treatments in Africa is needed by a complex interplay of technological, economic, regulatory, and ethical challenges. This paper examines the current landscape of nanoparticle-based therapies, identifying critical barriers to their adoption, including inadequate infrastructure, high costs, and insufficient regulatory frameworks. Technological deficiencies manifest as a need for advanced nanoparticle synthesis, delivery, and diagnostics equipment, impeding research and clinical applications. Economically, the high production costs of nanoparticles, compounded by limited access to advanced diagnostic and treatment facilities, create significant financial barriers for healthcare systems and patients alike. Additionally, the regulatory environment needs to be more cohesive, characterized by a lack of established protocols and expertise to evaluate the unique properties of nanomedicines. However, opportunities for advancement exist through focused research and development initiatives. Targeted drug delivery systems, early detection methods, and immunotherapy integration are promising avenues to enhance treatment outcomes. Collaborative partnerships between African institutions and international research entities, alongside public-private collaborations, could bolster local capabilities in nanomedicine. To facilitate the integration of nanoparticle-based therapies, African governments must prioritize funding for nanomedicine research, create robust regulatory frameworks, and ensure equitable access to these innovative treatments. A concerted effort involving policy reforms, investment, and collaboration is essential for overcoming existing barriers and realizing the full potential of nanoparticle-based therapies in improving health outcomes for gynecological cancer patients across Africa.

Indexed as

Genital Neoplasms, FemaleAfricaFemaleHumansNanomedicineNanoparticlesTheranostic NanomedicineAfricaGynecological cancersNanomedicineNanoparticle-based therapiesNanotheranosticsTargeted drug delivery

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.