ArticleScience advances2024
A bacterial methyltransferase that initiates biotin synthesis, an attractive anti-ESKAPE druggable pathway.
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Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15citing papers in PubMed
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Who cites it
15 citing papers in PubMed.
- Can we escape from top-priority ESKAPE pathogens?Emerging microbes & infections · 2026Review
- PARK7/HSPB1-Mediated Neuroprotective Effects of SHED in an In vitro Parkinson's Disease Model.Neurochemical research · 2026Article
- Mechanism and plasticity of primitive pyroptosis.Science advances · 2026Article
- Streptavidins Coordinate Biotin Sequestration and Self-Resistance Within a Biotin-Pathway Antibiotic Network.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Exploring the Link Between Biotin Metabolism andPathogens (Basel, Switzerland) · 2026Article
- Beyond antibiotics: Multidimensional interventions and coordinated governance against ESKAPE resistance.Biosafety and health · 2026Article
- Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A ferritin-like diiron oxygenase BioE initiates bacterial biotin synthesis, a promising antivirulence target.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Assembly and inhibition of transferable TMexCD1-TOprJ1 efflux pump.Nature communications · 2025Article
- The mechanisms of antibiotic resistance and drug resistance transmission of Klebsiella pneumoniae.The Journal of antibiotics · 2025Review
- Confronting the Antimicrobial Resistance Crisis in China: Emerging Superbugs, Genomic Surveillance, and Innovative Countermeasures.China CDC weekly · 2025Article
- Article
- Pathogenic bacteria enriched in the oral microbiota might be associated with recurrent pulmonary infections in elderly individuals.Aging clinical and experimental research · 2025Article
- Advanced nanotheranostic approaches for targeted glioblastoma treatment: a synergistic fusion of CRISPR-Cas gene editing, AI-driven tumor profiling, and BBB-modulation.Medical oncology (Northwood, London, England) · 2025Review
- Genome-wide identification of peanut ERFs and functional characterization of AhERF28 in response to salt and drought stresses.Plant cell reports · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Zhi SuKey Laboratory of Multiple Organ Failure (Ministry of Education), and Departments of Microbiology and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID 0009-0000-3767-4138
Weizhen ZhangShanghai Sci-Tech Inno Center for Infection & Immunity, State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Biochemistry and Biophysics, School of Life Science, Fudan University, Shanghai 200433, China.ORCID 0000-0002-7542-2772
Yu ShiKey Laboratory of Multiple Organ Failure (Ministry of Education), and Departments of Microbiology and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID 0000-0002-2266-2473
Tao CuiSchool of Life Sciences, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, China.
Yongchang XuKey Laboratory of Multiple Organ Failure (Ministry of Education), and Departments of Microbiology and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID 0000-0001-9554-7102
Runshi YangKey Laboratory of Multiple Organ Failure (Ministry of Education), and Departments of Microbiology and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID 0000-0002-6462-6139
Man HuangKey Laboratory of Multiple Organ Failure (Ministry of Education), and Departments of Microbiology and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID 0000-0002-0842-2254
Chun ZhouDepartment of Toxicology, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID 0000-0002-9257-468X
Huimin ZhangCancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-7352-8434
Ting LuDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-9043-3253
Jiuxin QuDepartment of Clinical Laboratory, Shenzhen Third People's Hospital, National Clinical Research Center for Infectious Diseases, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, Guangdong 518112, China.ORCID 0000-0003-1061-2353
Zheng-Guo HeCollege of Life Science and Technology, Guangxi University, Nanning, Guangxi 530004, China.ORCID 0000-0003-0945-4095
Jianhua GanShanghai Sci-Tech Inno Center for Infection & Immunity, State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Biochemistry and Biophysics, School of Life Science, Fudan University, Shanghai 200433, China.ORCID 0000-0002-8438-8852
Youjun FengKey Laboratory of Multiple Organ Failure (Ministry of Education), and Departments of Microbiology and General Intensive Care Unit of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID 0000-0001-8083-0175
Funding
No grant is acknowledged in the PubMed record.
Abstract
The covalently attached cofactor biotin plays pivotal roles in central metabolism. The top-priority ESKAPE-type pathogens,
Indexed as
Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsBiotinEnzyme InhibitorsKlebsiella pneumoniaeMethyltransferasesAdenosineAnimalsColistinCrystallography, X-RayMiceProtein BindingProtein Conformation, beta-StrandS-AdenosylhomocysteineAdenosineAnti-Bacterial AgentsBacterial ProteinsBiotinColistinEnzyme InhibitorsMethyltransferasesS-Adenosylhomocysteinesinefungin
Identifiers
What Socratic holds
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LicenceCC BY-NC
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.