Trial reportThorax2025
Smartphone application-based pulmonary rehabilitation in COPD: a multicentre randomised controlled trial.
Trial report in Thorax, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparative efficacy of different digital health intervention modalities versus traditional pulmonary rehabilitation on daily step counts and exercise capacity in patients with COPD: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- Effectiveness of Mobile Health-Based Self-Management Programs on Health-Related Outcomes in Patients With Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2025Pooled it
- Smartphone App-Based Music-Facilitated Pulmonary Rehabilitation Program Integrating Rhythm-Guided Walking and Singing for Patients With Chronic Obstructive Pulmonary Disease: Multicenter Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Patient perspectives on harmonica playing as an intervention for chronic obstructive pulmonary disease: a qualitative study.BMJ open · 2026Trial
- Clinical Efficacy of Smartphone App-Based Pulmonary Rehabilitation in Chronic Respiratory Diseases: Randomized Controlled and Feasibility Trials.Journal of medical Internet research · 2025Trial
- Is a Hybrid Pulmonary Rehabilitation Programme Feasible and Effective in Individuals With COPD After an Exacerbation-Related Hospitalisation: A Mixed Methods Study.Journal of clinical nursing · 2026Article
- Global trends and research hotspots in pulmonary rehabilitation for chronic obstructive pulmonary disease: a bibliometric analysis (2000-2024).Journal of thoracic disease · 2026Article
- Safety and Feasibility of an Asynchronous AI-Integrated Tele-Pulmonary Rehabilitation Application Among Patients with COPD.International journal of chronic obstructive pulmonary disease · 2026Article
- Global Trends of Cognition-Targeted Interventions in Chronic Lung Disease: A Bibliometric and Visualized Analysis.International journal of chronic obstructive pulmonary disease · 2026Review
- Development and Psychometric Evaluation of a Pulmonary Rehabilitation Information Needs Scale for Patients with Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2026Article
- Recent Advances in AI-Driven Mobile Health Enhancing Healthcare-Narrative Insights into Latest Progress.Bioengineering (Basel, Switzerland) · 2025Review
- Optimizing Treatment for Hospitalized Patients with COPD: A Study on the Impact of a LINE App-Based Multidisciplinary Team Approach Targeting Pharmacological Treatment, Lifestyle Changes, and Smoking Cessation.International journal of chronic obstructive pulmonary disease · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary rehabilitation (PR) is an essential element of chronic obstructive pulmonary disease (COPD) management. However, access to conventional face-to-face PR programmes is limited.
methodsThis multicentre, randomised controlled trial recruited patients with COPD from 18 sites in Germany and Switzerland, aiming to evaluate the impact of 12 weeks of a mobile app (intervention group; IVG) on quality of life, measured by COPD Assessment Test (CAT), and exercise capacity, assessed by 1-minute-sit-to-stand-test (1MSTST), compared with a control group (CTG) receiving 'enhanced standard-of-care'.
results278 patients were included in the study with a median age of 65 years (IQR 60-70) and forced expiratory volume in 1 s 48% predicted (IQR 37-60). In the intention-to-treat analysis at week 12, CAT improved from baseline by median -4 points versus -3 points in the IVG versus CTG groups, respectively (difference: 0 points (95% CI: -1, 2); p=0.7); 1MSTST improved by 1 vs 2 repetitions, respectively (difference: 1 repetition (95% CI: 0, 2); p=0.12)). In a subset of the IVG, with patients grouped by application adherence (≥3 days/week for≥75% of the weeks), adherent users (40.4%) improved 1MSTST versus non-adherent users by median 2 repetitions (95% CI: 1, 3]; p=0.006. Application use did not raise any safety concerns.
conclusionsApplication-based PR improved outcomes in COPD compared with baseline, and adherent users improved exercise capacity more compared with non-adherent users. Although not statistically significant compared with enhanced standard-of-care, this study may support the use of this application for COPD management and addresses the healthcare challenge of access to PR interventions. TRIAL REGISTRATION NUMBER: DRKS 00024390.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.